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Editorial Message and Issue Highlights–Vol. 16, No. 7–8, July-August 2019

Editorial Message and Issue Highlights–Vol. 16, No. 7–8, July-August 2019

| July 1, 2019

Dear Colleagues: Welcome to the July–August 2019 edition of Innovations in Clinical Neuroscience (ICNS). We start this issue with a meta-analysis by Whitlock, Woodward, and Alexander titled, “Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies.” Here, the authors investigated the accuracy of the popular theory that placebo […]

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Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies

Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies

| July 1, 2019

by Mark E. Whitlock, PhD; Philip W. Woodward, MPhil; and Robert C. Alexander, MD Dr. Whitlock is BioStatistics Head of Internal Medicine, Early Clinical Development, for Pfizer in Cambridge, United Kingdom. Mr. Woodward is an independent statistics consultant in Newmarket, United Kingdom. Dr. Alexander is with Takeda Pharmaceuticals International Company in Cambridge, Massachusetts. Funding: No […]

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High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure

High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure

| July 1, 2019

by Megan K. Skelly, PharmD, BCPS; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; and Claudia Lee, MD Drs. Skelly, Demler, and Lee are with the State University at Buffalo (SUNY) School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice in Buffalo, New York and Drs. Demler and Lee are also with New York […]

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Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child

Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child

| July 1, 2019

by Catherine Butz, PhD; Cindy Iske, MS, OTR/L; Natalie Truba, PhD; and Kristen Trott, PhD Drs. Butz, Truba, and Trott are with the Psychology Department, and Ms. Iske is Program Manager for the Rehabilitation Unit, Physical Medicine and Rehabilitation Service, at Nationwide Children’s Hospital in Columbus, Ohio. Funding: No funding was provided. Disclosures: The authors […]

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The Very Important Patient

The Very Important Patient

| July 1, 2019

by Danielle Gainer, MD, and Allison E. Cowan, MD Dr. Gainer is Assistant Professor, and Dr. Cowan is Associate Professor, in the Department of Psychiatry at Wright State University in Dayton, Ohio. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Department editors: Julie […]

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Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy

Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy

| July 1, 2019

by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine at Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine at Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided. Disclosures: The authors have no conflicts […]

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Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

| July 1, 2019

by Yue Deng, MSc; Brianna M. Marsh, BSc student; and Jackob Moskovitz, PhD Mr. Deng, Ms. Marsh, and Dr. Moskovitz are with the Department of Pharmacology and Toxicology at the School of Pharmacy, University of Kansas in Lawrence, Kansas. Funding: Support for the studies were provided by the KU ADC P30 AG035982 and the Landon […]

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Risk Management: Communicating with Family Members and Other Caregivers

Risk Management: Communicating with Family Members and Other Caregivers

| July 1, 2019

by Charles D. Cash, JD, LLM Mr. Cash is Assistant Vice President at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. This ongoing column is dedicated to providing information to our […]

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Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube

Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube

| July 1, 2019

Dear Editor: Social media platforms are increasingly used to disseminate health promotion and patient education.1–5 Impressions click-through rate (CTR) is the number of clicks on a health promotion and/or patient education ad, divided by the times the ad was shown on a social media platform. A recent study explored the practicality of Facebook advertising to […]

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ICNS July-August 2019 Digital Edition

ICNS July-August 2019 Digital Edition

| July 1, 2019

Click the cover below to access the July-August 2019 digital edition of Innovations in Clinical Neuroscience!

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