Synthetic Cannabinoids—”Spice” Can Induce a Psychosis: A Brief Review

| January 1, 2019

by Rajashekar Reddy Yeruva, MD; Hema Madhuri Mekala, MD; Meesha Sidhu MD; and Steven Lippmann, MD

Drs. Yeruva and Lippmann are with the University of Louisville School of Medicine in Louisville, Kentucky. Drs. Mekala and Sidhu are with Griffin Memorial Hospital in Norman, Oklahoma.

Funding: No funding was provided.

Disclosures: The authors have no conflicts of interest relevant to the content of this article.

Abstract: Synthetic cannabinoids, popularly called Spice, are common drugs of abuse in the United States. They are utilized as a substitute for marijuana, primarily for their psychoactive properties. Consumption has been rapidly increasing due to recreational effects, easy accessibility, and not being detectable by urine drug screening tests. The side effect profile of synthetic cannabinoids involves many organs and is not well known to the public. Psychoses are a common adverse result from their consumption. Primary care physicians and other medical professionals should consider synthetic cannabinoid consumption in the differential diagnoses of a patient presenting with psychosis.

Keywords: synthetic cannabinoids, Spice, K2, adverse events, psychosis, schizophrenia, long-term outcomes

Innov Clin Neurosci. 2019;16(1–2):31–32


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Category: Current Issue, Psychopharmacology, Review

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