Importance of Integrating Brain Health Conversations and Cognitive Assessments into Routine Checkups

The Association of Alzheimer’s Disease and Related Dementias Blood-Based Biomarkers With Depressive Symptoms

Research Summary: Depressive symptoms are common in older adults and have been associated with risk of Alzheimer’s disease and Alzheimer’s disease and related dementias (AD/ADRD), but the mechanisms and biomarkers underlying this relationship remain unclear. Prior studies have reported associations between depressive symptoms and AD/ADRD pathologies, sometimes before cognitive symptoms

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2026 AAN Annual Meeting Highlights

Rising mortality related to early-onset Alzheimer’s disease in the United States: trends and disparities, 2003–2023. This retrospective population-based study used Centers for Disease Control (CDC) and Prevention WONDER data to examine early-onset Alzheimer’s disease-related mortality (EOAD-RM) in the United States (US) from 2003 to 2023. Among 5,167 EOAD-related deaths, 62.4%

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Digital Resource Center

Upcoming educational events and digital resources related to Alzheimer’s disease Alzheimer’s Association International Conference 2026 July 12–15, 2026 London, United Kingdom * https://aaic.alz.org/   Autoimmune Neurology Conference August 7–8, 2026 Houston, Texas *https://www.aan.com/events/autoimmune-neurology-conference   American Neurological Association 2026 October 17–20, 2026 San Diego, California *https://myana.org/meetings/annual-meeting/   2026 Fall ADRC meeting

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Journal Watch: Alzheimer’s disease

Neuroplasticity and Alzheimer’s disease Gashtrodkhani AA, Shirkouhi SG, Khatami SS, et al. J Integr Neurosci. 2026;25(1):48051.  Summary. In a narrative review of literature investigating neuroplasticity related to Alzheimer’s disease, researchers found that pharmacological interventions might have therapeutic potential. Evidence showed that brain-derived neurotrophic factor and nerve growth factor mimetics, exercise,

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Enhancing Alzheimer Disease Detection Using Neuropsychiatric Symptoms: The Role of Mild Behavioral Impairment in the Revised NIA-AA Research Framework

Reprinted with permission. J Geriatr Psychiatry Neurol. 2026;39(3):277–287.* by Rebeca Leon, MSc; Maryam Ghahremani, PhD; Dylan X. Guan, BSc; Eric E. Smith, MD; Henrik Zetterberg, MD; and Zahinoor Ismail, MD Drs. Leon, Ghahremani, Guan, Smith, and Ismail are with Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada. Drs. Ghahremani

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