Innovations in Clinical Neuroscience
Providing evidence-based information in a practical, easy-to-read format for practicing clinicians, investigators, industry scientists, and other entities involved in the field of neuroscience
VOLUME 20, ISSUE 1–3, JANUARY-MARCH 2023

Letter to the Editor: Bipolar I Disorder Exacerbation and COVID-19 Vaccination: Correspondence
Funding/financial disclosures. The authors have no conflict of interest relevant to the content of this letter. No funding was received for the preparation of this letter. Innov Clin Neurosci. 2023;20(1–3):8. Dear Editor: We would like to discuss the article, “Bipolar I Disorder Exacerbation Following COVID-19 Vaccination,”1 wherein Guina et al1 described the cases of a […]

Letter to the Editor: Antipsychotics and Parkinson’s Disease: A Troubling Mix
Funding/financial disclosures. The authors have no conflict of interest relevant to the content of this letter. Our studies are supported by the following grants: Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Innov Clin […]

Remote Cognitive Therapeutic Exercise in Facial Nerve Palsy Rehabilitation: Pandemic Tips and Tricks
by Filippo Cavallaro, PT; Simona Portaro, MD, PhD; Teresa Pintaudi, PT; Mariachiara Ceccio, PT; and Angelo Alito, MD All authors are with the University of Messina in Messina, Italy. Funding: No funding was provided for this article. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Innov Clin Neurosci. […]
PAST ARTICLES

The Role of Transcranial Magnetic Stimulation as a Surrogate Marker of Disease Activity in Patients with Multiple Sclerosis: A Literature Review
by Muhannad M. Alsharidah, MBBS; Mohammad Uzair, BS; Sarah S. Alseneidi, MBBS; Afnan A. Alkharan, MBBS; Reem Fahd Bunyan, MBBS; and Shahid Bashir, PhD Drs. Alsharidah and Alseneidi are with the College of Medicine, King Saud University in Riyadh, Saudi Arabia. Mr. Uzair is with the Department of Biological Sciences, Faculty of Basic and Applied […]

Toward Improving Functional Recovery in AIDS-associated Progressive Multifocal Leukoencephalopathy: A Single Case Pilot Study on a Novel Neuromodulation Approach
by Antonino Naro, MD, PhD; Luana Billeri, MSc; Paola Lauria, MSc; Alfredo Manuli, MSc; and Rocco Salvatore Calabrò, MD Drs. Naro and Calabrò, Ms. Billeri, Ms. Lauria, and Mr. Manuli are with IRCCS Centro Neurolesi Bonino Pulejo–Piemonte in Messina, Italy. Funding: No funding was provided for this study. Disclosures: The authors have no conflicts […]

Could Palmitoylethanolamide Be an Effective Treatment for Long-COVID-19? Hypothesis and Insights in Potential Mechanisms of Action and Clinical Applications
by Loredana Raciti, MD, PhD; Francesca Antonia Arcadi, MD, PhD; and Rocco Salvatore Calabrò, MD, PhD Drs. Raciti, Arcadi, and Calabrò are with IRCCS Centro Neurolesi “Bonino Pulejo” in Messina, Italy. Funding: No funding was provided for this study. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Innov […]
PSYCHOTHERAPY ROUNDS

Existential Issues in Psychotherapy
by Brent Schnipke, MD, and Michael MacKay, DO Both authors are with Wright State University Boonshoft School of Medicine in Dayton, Ohio. Funding: No funding was provided for this study. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Innov Clin Neurosci. 2023;20(1–3):72–75. Department Editor Julie P. Gentile, MD, […]

Psychotherapy for Adult ADHD
by Kari Harper, MD, and Julie P. Gentile, MD, MBA Dr. Harper is Assistant Professor and Dr. Gentile is Professor and Chair of the Department of Psychiatry at Wright State University in Dayton, Ohio. Funding: No funding was provided for this study. Disclosures: The authors have no conflicts of interest relevant to the content of […]

Personality Disorders in Patients with Intellectual Disability
by Julie P. Gentile MD, MBA; Nita V. Bhatt MD, MPH; Jesse P. Cannella, BS; Kari Harper, MD; and John Johnson, MD, MBA Dr. Gentile is Professor and Chair of the Department of Psychiatry at Wright State University in Dayton, Ohio. Dr. Bhatt is Associate Professor and Associate Clerkship Director at Wright State University in […]
Schizophrenia

Xanomeline and Trospium: A Potential Fixed Drug Combination (FDC) for Schizophrenia—A Brief Review of Current Data
by Alok Singh, MD Dr. Singh is with All India Institute of Medical Sciences in Raipur, India. Funding: No funding was provided for this study. Disclosures: The author has no conflicts of interest relevant to the contents of this article. Innov Clin Neurosci. 2022;19(10–12):43–47. Abstract Xanomeline, a cholinergic agonist, was initially evaluated for the treatment […]

Impact of Lurasidone on Metabolic Parameters and Prolactin Levels Based on Differences of Psychiatric Diagnosis, Dosage, and Introducing Methods: An Observational Study
by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine, Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine, Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided for this study. Disclosures: The authors have no […]

Effects of Clozapine on Neurocognitive Functions in Schizophrenia: A Naturalistic Comparison to Non-clozapine Antipsychotics
by JP Lindenmayer, MD; Beverly J. Insel, PhD; Anzalee Khan, PhD; McKenzie Osborne, BA; Abraham Goldring, MA; and Mary Seddo, BA Drs. Lindenmayer, Insel, and Khan, Ms. Osborne and Seddo, and Mr. Goldring are with Manhattan Psychiatric Center in New York City, New York. Drs. Lindenmayer and Khan and Mr. Goldring are with Nathan S. […]
Risk Management

Risk Management: “Covering” Your Bases: Managing Risk While Away from Your Practice or Filling in for a Colleague
by Ann L. McNary, JD Ms. McNary is a Senior Risk Manager at Professional Risk Management Services (PRMS). Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS. PRMS manages a professional liability insurance program for psychiatrists. Innov Clin Neurosci. 2023;20(1–3):76–77. This ongoing column is dedicated […]

Risk Management: Top 25 Tips to Reduce Clinicians’ Stress Levels
by Donna Vanderpool, MBA, JD Ms. Vanderpool is the Director of Risk Management at Professional Risk Management Services (PRMS). Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS. PRMS manages a professional liability insurance program for psychiatrists. Innov Clin Neurosci. 2022;19(10–12):58–59. This ongoing column is […]

Risk Management: On the Record: Documentation of Psychiatric Treatment
by Ann L. McNary, JD Ms. McNary is Senior Risk Manager at Professional Risk Management Services (PRMS). Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS. PRMS manages a professional liability insurance program for psychiatrists. Innov Clin Neurosci. 2022;19(7–9):77–79. This ongoing column is dedicated to providing information […]
Trial Methodology

CNS Summit 2022 Abstracts of Poster Presentations
A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research presented during the CNS Summit 2022 event. The supplement is also available online by visiting www.innovationscns.com. […]

CNS Summit 2021 Abstracts of Poster Presentations
A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research presented during the CNS Summit 2021 event. The supplement is also available online by visiting www.innovationscns.com. […]

CNS Summit 2020 Abstracts of Poster Presentations
A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that was presented during the CNS Summit 2020 event. The supplement is also available online by […]
Recent Posts

Gender-affirming Care for Transgender Patients
by Nita Bhatt MD, MPH; Jesse Cannella, MSIII; and Julie P. Gentile, MD, MBA Dr. Bhatt is Associate Director of Medical Student Education and Associate Professor in the Department of Psychiatry at Wright State University in Dayton, Ohio. Mr. Cannella is a medical student at Wright State University Boonshoft School of Medicine in Dayton, Ohio. […]

Special Challenges in Pediatric Drug Development: First of Three Sets of Expanded Proceedings from the ISCTM Autumn Conference on Pediatric Drug Development
by Philip D. Harvey, PhD; Joan Busner, PhD; Gahan Pandina, PhD; H. Gerry Taylor, PhD; Meg Grabb, PhD; and Joohi Jimenez-Shahed, MD Dr. Harvey is with Department of Psychiatry, University of Miami Miller School of Medicine in Miami, Florida. Dr. Busner is with Signant Health in Blue Bell, Pennsylvania and Department of Psychiatry, Virginia Commonwealth […]

Implications of Pediatric Initiatives on CNS Drug Development for All Ages—2020 and Beyond: Second of Three Sets of Expanded Proceedings from the 2020 ISCTM Autumn Conference on Pediatric Drug Development
by Gahan Pandina, PhD; Joan Busner, PhD; Joseph P. Horrigan, MD; Christine McSherry, RN, BSN; Alison Bateman-House, MA, MPH, PhD; Luca Pani, MD; and Judith Kando, PharmD, BCPP Dr. Pandina is with Janssen Pharmaceuticals in Titusville, New Jersey. Dr. Busner is with Signant Health in Blue Bell, Pennsylvania and Department of Psychiatry, Virginia Commonwealth University School […]

Patient Centricity: Design and Conduct of Clinical Trials in Orphan Diseases: Third of Three Sets of Expanded Proceedings from the 2020 ISCTM Autumn Conference on Pediatric Drug Development
by Joan Busner, PhD; Gahan Pandina, PhD; Simon Day, PhD; Atul Mahableshwarkar, MD; Lucas Kempf, MD; Maria Sheean, MD; and Judith Dunn, PhD Dr. Busner is with Signant Health in Blue Bell, Pennsylvania and Department of Psychiatry, Virginia Commonwealth University School of Medicine in Richmond, Virginia. Dr. Pandina is with Janssen Pharmaceuticals in Titusville, New Jersey. Dr. […]

Exploring the Impact of COVID-19 Vaccination on Patients Taking Clozapine
by Tammie Lee Demler, PharmD, MBA, BCGP, BCPP; and Carolyn O’Donnell, PharmD, PGY-2 Drs. Demler and O’Donnell are with the New York State Office of Mental Health at Buffalo Psychiatric Center and State University of New York at Buffalo School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice in Buffalo, New York. Dr. Demler is […]

WAVES: A Novel Test to Evaluate Visuospatial Construction Ability in a School-aged Population
by Franco Di Cesare, MD; Cristiana Di Carlo, MSc; and Leonardo Di Cesare, MD Drs. F. Di Cesare and Di Carlo are with Leoben Research srl in Rome, Italy. Dr. L. Di Cesare is with Glaxo-Smith-Kline in Siena, Italy. Funding: The project was sponsored and funded by Leoben Research. Disclosures: Drs. F. Di Cesare and Di […]