Innovations in Clinical Neuroscience

Providing evidence-based information in a practical, easy-to-read format for practicing clinicians, investigators, industry scientists, and other entities involved in the field of neuroscience

VOLUME 17, ISSUE 7–9, JULY-SEPTEMBER 2020

Meralgia Paresthetica Successfully Treated with Palmithoylethanolamide

Meralgia Paresthetica Successfully Treated with Palmithoylethanolamide

by Rocco Salvatore Calabrò MD, PhD; Carmela Casella, MD;  Alfredo Manuli, MSc; David Militi, MD; and Giuseppe Gervasi, MD, PhD Drs. Calabrò and Manuli are with IRCCS Centro Neurolesi “Bonino Pulejo” in Messina, Italy. Dr. Casella is with Policlinico University in Messina, Italy. Dr. Militi is with Stomato-dental Laboratory in Messina, Italy. Dr. Gervasi is […]

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A Flash of Hope: Eye Movement Desensitization and Reprocessing

A Flash of Hope: Eye Movement Desensitization and Reprocessing

by Danielle Gainer, MD; Sarah Alam, BS; Harris Alam; and Hannah Redding, BA Dr. Gainer, Sarah Alam, and Ms. Redding are with Wright State University Boonshoft School of Medicine in Fairborn, Ohio. Harris Alam is with University of Central Florida in Orlando, Florida. FUNDING: No funding was provided. DISCLOSURES: The authors have no conflicts of […]

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Behavioral Activation Contributed to the Total Reduction of Depression Symptoms in the Smartphone-based Cognitive Behavioral Therapy: A Secondary Analysis of a Randomized, Controlled Trial

Behavioral Activation Contributed to the Total Reduction of Depression Symptoms in the Smartphone-based Cognitive Behavioral Therapy: A Secondary Analysis of a Randomized, Controlled Trial

by Hissei Imai, MD, PhD; Mitsuhiko Yamada, MD, PhD; Masatoshi Inagaki, MD, PhD; Norio Watanabe, MD, PhD; Bun Chino, MD, PhD; Akio Mantani, MD, PhD; and Toshiaki A Furukawa, MD, PhD Drs. Imai, Watanabe, and Furukawa are with the Department of Health Promotion of Human Behavior at Kyoto University Graduate School of Medicine / School […]

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Schizophrenia

Role of Norepinephrine in Schizophrenia: An Old-fashioned but New Story from Emergency Medicine

Role of Norepinephrine in Schizophrenia: An Old-fashioned but New Story from Emergency Medicine

Dear Editor: A number of hypotheses have been put forth regarding the etiology of schizophrenia, including dopamine hypothesis and glutamate hypothesis.1 However, a lesser known theory is that elevated norepinephrinergic signaling plays a causative role in schizophrenia.2 We treated a patient with septic shock schizophrenia who developed delusions and hallucinations following continuous norepinephrine infusion. This […]

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The Role of Serum Lithium Concentration on Pill Burden in Psychiatric Populations

The Role of Serum Lithium Concentration on Pill Burden in Psychiatric Populations

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Scam Susceptibility in a Young, Schizoaffective Patient with Traumatic Brain Injury: A Case Report with a Review of Financial Exploitation Literature and Possible Therapeutic Interventions Gleaned from Traumatic Brain Injury Rehabilitation Research

Scam Susceptibility in a Young, Schizoaffective Patient with Traumatic Brain Injury: A Case Report with a Review of Financial Exploitation Literature and Possible Therapeutic Interventions Gleaned from Traumatic Brain Injury Rehabilitation Research

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Risk Management

Risk Management: Top Five HIPAA Lessons Learned: A Review of HHS Resolution Agreements

Risk Management: Top Five HIPAA Lessons Learned: A Review of HHS Resolution Agreements

by Justin Pope, JD Mr. Pope is  an Associate Risk Manager at Professional Risk Management Services (PRMS). FUNDING: No funding was provided for the preparation of this article. DISCLOSURES: The author is an employee of PRMS Inc., a risk-management consulting company for health care providers. This ongoing column is dedicated to providing information to our […]

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Risk Management: Emergency Planning

Risk Management: Emergency Planning

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Navigating the ADA: What Clinicians Need to Know—Part Two

Navigating the ADA: What Clinicians Need to Know—Part Two

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Cognition

Frontiers in Detecting Consciousness: The Growing Use of EEG Analysis

Frontiers in Detecting Consciousness: The Growing Use of EEG Analysis

Dear Editors: There is growing scientific interest regarding the use of electroencephalogram (EEG) and multivariate analysis as a means to classify states of consciousness. A recent work assessed the validity of 28 potential EEG markers of consciousness, using the Disorders of Consciousness (DoC)-Forest (the name of the algorithm) tool, to establish states of awareness in […]

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Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

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Does Vitamin D Deficiency Contribute to Cognitive Dysfunction in Patients with Systemic Lupus Erythematosus?

Does Vitamin D Deficiency Contribute to Cognitive Dysfunction in Patients with Systemic Lupus Erythematosus?

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Recent Posts

Latency to First Event is Shorter in Psychogenic Non-epileptic Seizures Than in Epileptic Seizures in an Epilepsy Monitoring Unit

Latency to First Event is Shorter in Psychogenic Non-epileptic Seizures Than in Epileptic Seizures in an Epilepsy Monitoring Unit

| July 1, 2020

by Vishwanath Sagi MBBS, MPH; Jaime Shoup MD; Ravikiran Chilukuri; and M. Steven Evans MD  Drs. Sagi and Evans are with the Department of Neurology at the University of Louisville in Louisville, Kentucky. Drs. Shoup and Chilukuri are with the University of Louisville School of Medicine in Louisville, Kentucky. FUNDING: No funding was provided for […]

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The Depression Inventory Development Scale:  Assessment of Psychometric Properties Using Classical and Modern Measurement Theory in a CAN-BIND Trial

The Depression Inventory Development Scale: Assessment of Psychometric Properties Using Classical and Modern Measurement Theory in a CAN-BIND Trial

| July 1, 2020

by Anthony L. Vaccarino, PhD; Amir H. Kalali, MD; Pierre Blier, MD, PhD; Susan Gilbert Evans, MSc; Nina Engelhardt, PhD; Jane A. Foster, PhD; Benicio N. Frey, MD, PhD; John H. Greist, MD; Kenneth A. Kobak, PhD; Raymond W. Lam, MD, FRCPC; Glenda MacQueen, MD, PhD, FRCPC; Roumen Milev, MD, PhD, FRCPsych, FRCPC; Daniel J. […]

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Layperson/Plain Language Summaries: Can Sponsors, CROs, and Sites Deliver in 2020?

Layperson/Plain Language Summaries: Can Sponsors, CROs, and Sites Deliver in 2020?

| July 1, 2020

by Charles S. Wilcox, PhD, MPA, MBA; Leslie Franceschi, BA; and ADAM SIMMONS, MPH Dr. Wilcox is Chief Executive Officer at Praxis Research Consulting in Newport Beach, California. Ms. Franceschi is Senior Project Director at Syneos Health in Morrisville, North Carolina. Mr. Simmons is Director of Clinical Program Management at Alkermes Inc. in Boston, Massachusetts. […]

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