Innovations in Clinical Neuroscience

Providing evidence-based information in a practical, easy-to-read format for practicing clinicians, investigators, industry scientists, and other entities involved in the field of neuroscience

VOLUME 19, ISSUE 7–9, JULY-SEPTEMBER 2022

Letter to the Editor: Steroid Management in a Patient with Myasthenia Gravis Undergoing COVID-19 Vaccination

Letter to the Editor: Steroid Management in a Patient with Myasthenia Gravis Undergoing COVID-19 Vaccination

Funding/financial disclosures. The authors have no conflict of interest relevant to the content of this letter. No funding was received for the preparation of this letter. Innov Clin Neurosci. 2022;19(7–9):8.   Dear Editor: We report the case of a 70-year-old patient affected by ocular myasthenia gravis (MG), diagnosed three years ago due to double vision […]

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Bipolar I Disorder Exacerbation Following COVID-19 Vaccination

Bipolar I Disorder Exacerbation Following COVID-19 Vaccination

by Jeffrey Guina, MD; Sara Barlow, BS; and Duren Gutierrez, DNP Dr. Guina and Ms. Barlow are with Oakland University William Beaumont School of Medicine in Rochester, Michigan. Drs. Guina and Gutierrez are with Easterseals Michigan, Medical Services in Auburn Hills, Michigan. Dr. Guina is with Beaumont Health Psychiatry Residency, Graduate Medical Education in Southfield, […]

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Post-stroke Sexual Dysfunction in Men: Epidemiology, Diagnostic Work-up, and Treatment

Post-stroke Sexual Dysfunction in Men: Epidemiology, Diagnostic Work-up, and Treatment

by Rocco Salvatore Calabrò, MD, PhD  Dr. Calabrò is with IRCCS Centro Neurolesi “Bonino-Pulejo” in Messina, Italy. Funding: No funding was provided for this article. Disclosures: The author has no conflicts of interest relevant to the content of this article. Innov Clin Neurosci. 2022;19(7–9):12–16. Abstract Stroke is a leading cause of death and disability throughout […]

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PAST ARTICLES

The Role of Transcranial Magnetic Stimulation as a Surrogate Marker of Disease Activity in Patients with Multiple Sclerosis: A Literature Review

The Role of Transcranial Magnetic Stimulation as a Surrogate Marker of Disease Activity in Patients with Multiple Sclerosis: A Literature Review

by Muhannad M. Alsharidah, MBBS; Mohammad Uzair, BS; Sarah S. Alseneidi, MBBS; Afnan A. Alkharan, MBBS; Reem Fahd Bunyan, MBBS; and Shahid Bashir, PhD Drs. Alsharidah and Alseneidi are with the College of Medicine, King Saud University in Riyadh, Saudi Arabia. Mr. Uzair is with the Department of Biological Sciences, Faculty of Basic and Applied […]

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Toward Improving Functional Recovery in AIDS-associated Progressive Multifocal Leukoencephalopathy: A Single  Case Pilot Study on a Novel Neuromodulation Approach

Toward Improving Functional Recovery in AIDS-associated Progressive Multifocal Leukoencephalopathy: A Single Case Pilot Study on a Novel Neuromodulation Approach

by Antonino Naro, MD, PhD; Luana Billeri, MSc; Paola Lauria, MSc; Alfredo Manuli, MSc; and Rocco Salvatore Calabrò, MD  Drs. Naro and Calabrò, Ms. Billeri, Ms. Lauria, and Mr. Manuli are with IRCCS Centro Neurolesi Bonino Pulejo–Piemonte in Messina, Italy. Funding: No funding was provided for this study.   Disclosures: The authors have no conflicts […]

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Could Palmitoylethanolamide Be an Effective Treatment for Long-COVID-19? Hypothesis and Insights in Potential Mechanisms of Action and Clinical Applications

Could Palmitoylethanolamide Be an Effective Treatment for Long-COVID-19? Hypothesis and Insights in Potential Mechanisms of Action and Clinical Applications

by Loredana Raciti, MD, PhD; Francesca Antonia Arcadi, MD, PhD; and Rocco Salvatore Calabrò, MD, PhD Drs. Raciti, Arcadi, and Calabrò are with IRCCS Centro Neurolesi “Bonino Pulejo” in Messina, Italy. Funding: No funding was provided for this study.   Disclosures: The authors have no conflicts of interest relevant to the content of this article.  Innov […]

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PSYCHOTHERAPY ROUNDS

Personality Disorders in Patients with Intellectual Disability

Personality Disorders in Patients with Intellectual Disability

by Julie P. Gentile MD, MBA; Nita V. Bhatt MD, MPH; Jesse P. Cannella, BS; Kari Harper, MD; and John Johnson, MD, MBA Dr. Gentile is Professor and Chair of the Department of Psychiatry at Wright State University in Dayton, Ohio. Dr. Bhatt is Associate Professor and Associate Clerkship Director at Wright State University in […]

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Psychotherapy for Violent Behavior in Children and Adolescents

Psychotherapy for Violent Behavior in Children and Adolescents

by Kari Harper, MD, and Julie P. Gentile, MD, MBA Dr. Harper is Assistant Professor and Assistant Training Director of Child/Adolescent Fellowship at Wright State University in Dayton, Ohio. Dr. Gentile is Professor and Chair of the Department of Psychiatry at Wright State University in Dayton, Ohio. Funding: No funding was provided for this study. […]

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Gender-affirming Care for Transgender Patients

Gender-affirming Care for Transgender Patients

by Nita Bhatt MD, MPH; Jesse Cannella, MSIII; and Julie P. Gentile, MD, MBA Dr. Bhatt is Associate Director of Medical Student Education and Associate Professor in the Department of Psychiatry at Wright State University in Dayton, Ohio. Mr. Cannella is a medical student at Wright State University Boonshoft School of Medicine in Dayton, Ohio. […]

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Schizophrenia

Impact of Lurasidone on Metabolic Parameters and Prolactin Levels Based on Differences of Psychiatric Diagnosis, Dosage, and Introducing Methods: An Observational Study

Impact of Lurasidone on Metabolic Parameters and Prolactin Levels Based on Differences of Psychiatric Diagnosis, Dosage, and Introducing Methods: An Observational Study

by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine, Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine, Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided for this study.  Disclosures: The authors have no […]

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Effects of Clozapine on Neurocognitive Functions in Schizophrenia: A Naturalistic Comparison to Non-clozapine Antipsychotics

Effects of Clozapine on Neurocognitive Functions in Schizophrenia: A Naturalistic Comparison to Non-clozapine Antipsychotics

by JP Lindenmayer, MD; Beverly J. Insel, PhD; Anzalee Khan, PhD; McKenzie Osborne, BA; Abraham Goldring, MA; and Mary Seddo, BA Drs. Lindenmayer, Insel, and Khan, Ms. Osborne and Seddo, and Mr. Goldring are with Manhattan Psychiatric Center in New York City, New York. Drs. Lindenmayer and Khan and Mr. Goldring are with Nathan S. […]

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Anatomical Association Between Schizophrenia and Cerebellum

Anatomical Association Between Schizophrenia and Cerebellum

by Rajashekar Reddy Yeruva, MD; Yafei Shang, MD; Ben Schoenbachler, MD; Sharon Nuss, MS; and Rif S El-Mallakh, MD Dr. Yeruva is with Baylor Scott and White Medical Center in Round Rock, Texas. Drs. Shang, Schoenbachler, El-Mallakh, and Sharon Nuss are with the University of Louisville School of Medicine in Louisville, Kentucky. FUNDING: No funding […]

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Risk Management

Risk Management: On the Record: Documentation of Psychiatric Treatment

Risk Management: On the Record: Documentation of Psychiatric Treatment

by Ann L. McNary, JD Ms. McNary is Senior Risk Manager at Professional Risk Management Services (PRMS). Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS. PRMS manages a professional liability insurance program for psychiatrists. Innov Clin Neurosci. 2022;19(7–9):77–79. This ongoing column is dedicated to providing information […]

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Risk Management: Adjusting to Your New Normal

Risk Management: Adjusting to Your New Normal

by Ann L. McNary, JD Ms. McNary is Senior Risk Manager at Professional Risk Management Services (PRMS). Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS. PRMS manages a professional liability insurance program for psychiatrists. Innov Clin Neurosci. 2022;19(4–6):87–89. This ongoing column is dedicated to […]

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Risk Management: Responding to Record Requests: The Basics

Risk Management: Responding to Record Requests: The Basics

by Ann L. McNary, JD Ms. McNary is Senior Risk Manager at Professional Risk Management Services (PRMS) Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS. PRMS manages a professional liability insurance program for psychiatrists. Innov Clin Neurosci. 2022;19(1–3):71–73. This ongoing column is dedicated to […]

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Cognition

Development of a Cognitive Ability Assessment Tool for a Pediatric School-aged Population

Development of a Cognitive Ability Assessment Tool for a Pediatric School-aged Population

by Franco Di Cesare, MD; Leonardo Di Cesare; and Cristiana Di Carlo, MSc  Dr. F. Di Cesare, Mr. L. Di Cesare, and Ms. Di Carlo are with Leoben Research srl in Rome, Italy. FUNDING: This study was supported by Leoben Research.  DISCLOSURES: The authors are employed by Leoben Research.  Innov Clin Neurosci. 2021;18(10–12):30–37. ABSTRACT: Objective. […]

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Frontiers in Detecting Consciousness: The Growing Use of EEG Analysis

Frontiers in Detecting Consciousness: The Growing Use of EEG Analysis

Dear Editors: There is growing scientific interest regarding the use of electroencephalogram (EEG) and multivariate analysis as a means to classify states of consciousness. A recent work assessed the validity of 28 potential EEG markers of consciousness, using the Disorders of Consciousness (DoC)-Forest (the name of the algorithm) tool, to establish states of awareness in […]

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Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

by Yue Deng, MSc; Brianna M. Marsh, BSc student; and Jackob Moskovitz, PhD Mr. Deng, Ms. Marsh, and Dr. Moskovitz are with the Department of Pharmacology and Toxicology at the School of Pharmacy, University of Kansas in Lawrence, Kansas. Funding: Support for the studies were provided by the KU ADC P30 AG035982 and the Landon […]

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Recent Posts

July–September 2022 Digital Edition

July–September 2022 Digital Edition

| July 1, 2022

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Pre-, Peri-, and Neonatal Factors Associated with Autism Spectrum Disorder: Results of a Lebanese Case-control Study

Pre-, Peri-, and Neonatal Factors Associated with Autism Spectrum Disorder: Results of a Lebanese Case-control Study

| July 1, 2022

by Aline Hajj, PharmD, PhD; Souheil Hallit, PharmD, MSc, MPH, PhD; Rouba El-Khatib, PharmD; Sandra Abi Haidar, PharmD; Fabienne Hajj Moussa Lteif, MSc; Layal Hajj, MSc; Maguy Moudawar, MSc; and Lydia Rabbaa Khabbaz, PharmD, PhD Drs. A. Hajj, El-Khatib, Abi Haidar, and Rabbaa Khabbaz are with the Faculty of Pharmacy, Saint-Joseph University in Beirut, Lebanon. […]

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Quantitative Characterization of the Smoothness of Extended-release Methylphenidate Pharmacokinetic Profiles

Quantitative Characterization of the Smoothness of Extended-release Methylphenidate Pharmacokinetic Profiles

| July 1, 2022

by Michelle D. Po, PhD; Roberto Gomeni, PhD, HDR, FCP; and Bev Incledon, PhD Dr. Po is with Highland Therapeutics Inc. in Toronto, Ontario, Canada. Dr. Gomeni is with PharmacoMetrica France in La Fouillade, France and is an Adjunct Professor with the Division of Pharmacotherapy and Experimental Therapeutics in the UNC Eshelman School of Pharmacy at […]

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