Tag: biomarkers

Letters to the Editor: What About Biomarkers for Parkinson’s Disease?
Dear Editor: Parkinson’s disease (PD) affects over 600,000 patients in the United States; these numbers might double by 2040, as the population of older people increases.1 Diagnostic clues include the signs of resting tremor, bradykinesia, muscle rigidity, and postural imbalance. However, these clinical indicators might be inaccurate much of the time. A low rate of […]

Longitudinal Data in Patients with Niemann-Pick Type C Disease Under Combined High Intrathecal and Low Intravenous Dose of 2-hydroxylpropyl-β-cyclodextrin
by Evangelia Bountouvi, MD, PhD; Melpomeni Giorgi, MD; Anna Papadopoulou, PhD; Kaj Blennow, PhD; Ingemar Björkhem, PhD; Maria Tsirouda, PhD; Spyridon Kanellakis, Msc, PhD; Andreas Fryganas, MD; Maria Spanou, MD; Ioanna Georgaki, MD; Sofia Asprogeraka, MD; and Argyrios Dinopoulos, PhD Drs. Bountouvi, Giorgi, Papadopoulou, Tsirouda, Fryganas, Spanou, Georgaki, Asprogeraka, and Dinopoulos are with the Third […]

Single Nucleotide Polymorphisms and the Central Nervous System: Potential Biomarkers in Identifying Suicide Risk
by Atmaram Yarlagadda, MD; Kevin P. Rosenblatt, MD, PhD; and Anita H. Clayton, MD Dr. Yarlagadda is Chief, Behavioral Health Services, McDonald Army Health Center in Newport News, Virginia, and Assistant Professor, Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia; Dr. Rosenblatt is Adjunct Associate Professor, UT Health at Houston, Department of […]

Clinical Implications of the New Diagnostic Guidelines for Dementia
by Edmund Howe, MD, JD Dr. Howe is Professor, Department of Psychiatry, Director, Programs in Medical Ethics, and Senior Scientist, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, Maryland. Innov Clin Neurosci. 2013;10(5–6):32–38