Dr. Bert Vargas speaks with Dr. Kavita Nair to discuss dementia risk factors and the importance of making brain health a routine part of preventive care before cognitive symptoms emerge. She reviews considerations around APOE testing, emphasizing the value of involving primary care clinicians or genetic counselors and using genetic risk information alongside modifiable risk factors such as cardiovascular health, physical activity, and social engagement. Dr. Nair also explores how family history, socioeconomic factors, education, and other social determinants of health can influence cognitive health, while distinguishing cognitive health as one component of broader brain health. The discussion highlights the need to normalize these conversations and determine how proactive brain health assessment can be incorporated more consistently into clinical practice.