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Letter to the Editor: Valproate-Induced Hyperammonemic Encephalopathy—A Case Report

Vikas Mangewala, MD; Sajjad Sarwar, MD; Ryan Rosenberger; Theodor Rais, MD; and Michele Knox, PhD Drs. Mangewala and Sarwar are Fellows, Child and Adolescent Psychiatry; Mr. Rosenberger is a medical

Defining a Clinically Meaningful Effect for the Design and Interpretation of Randomized Controlled Trials

by Richard S. E. Keefe, PhD; Helena C. Kraemer, PhD; Robert S. Epstein, MD, MS; Ellen Frank, PhD; Ginger Haynes, PhD; Thomas P. Laughren, MD; James McNulty, AbScB; Shelby D.

How Can Registries Contribute to the Development and Evaluation of CNS Therapeutics?

by Joanne B. Severe, MS, and Annette Stemhagen, DrPH, FISPE Ms. Severe is a research consultant in Rockville, Maryland, and Dr. Stemhagen is with United Biosource Corp. in Bethesda, Maryland.

Editor’s Message and Issue Highlights, April 2013

Dear Colleagues: Welcome to the April issue of Innovations in Clinical Neuroscience. This month, we lead with a topic we are covering for the first time in the journal and