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Defining a Clinically Meaningful Effect for the Design and Interpretation of Randomized Controlled Trials

by Richard S. E. Keefe, PhD; Helena C. Kraemer, PhD; Robert S. Epstein, MD, MS; Ellen Frank, PhD; Ginger Haynes, PhD; Thomas P. Laughren, MD; James McNulty, AbScB; Shelby D.

How Can Registries Contribute to the Development and Evaluation of CNS Therapeutics?

by Joanne B. Severe, MS, and Annette Stemhagen, DrPH, FISPE Ms. Severe is a research consultant in Rockville, Maryland, and Dr. Stemhagen is with United Biosource Corp. in Bethesda, Maryland.

Editor’s Message and Issue Highlights, April 2013

Dear Colleagues: Welcome to the April issue of Innovations in Clinical Neuroscience. This month, we lead with a topic we are covering for the first time in the journal and

Poverty and Language Development: Roles of Parenting and Stress

by Suzanne C. Perkins, Eric D. Finegood, and James E. Swain Dr. Perkins is from Department of Psychiatry, Faculty of Medicine, University of Michigan, Ann Arbor, Michigan; Mr. Finegood is