Dear Colleagues:

Welcome to the August issue of Innovations in Clinical Neuroscience.

Sansone and Sansone take a look at data on the occurrence of college-aged individuals faking symptoms of attention deficit hyperactivity disorder in order to have access stimulant medication. Available literature shows that this is a realistic concern that psychiatrists, primary care physicians, and campus healthcare professionals should be made aware.

Next, Sarwar and McGinnis share an interesting case of dissociative disorder that appeared to be linked to use of topiramate in a 21-year-old female patient. The authors discuss possible reasons for this potential link.

Following this, Ejaz et al provide a comprehensive review of the association between obstructive sleep apnea (OSA) and depression. The authors review the literature and describe and discuss the overlap of symptoms between OSA and depression and how untreated OSA may cause antidepressant failure in depressed patients. The authors explore the potential link between the two disorders and describe several possible pathophysiological mechanisms that could explain how OSA can cause or worsen depression.

Next, Gopal et al share a post-hoc analysis of efficacy data for time points before and after the first 28 days of a 13-week acute schizophrenia study that compared paliperidone palmitate to oral risperidone during initiation of long-acting injectable risperidone. The authors found that during the first month of the 13-week study, paliperidone palmitate without oral supplementation had similar efficacy and safety to oral risperidone (during initiation of risperidone long-acting injectable) in acutely exacerbated schizophrenia.

Following this, Yarlagadda et al share results of a small study in which blood samples were collected from normal controls, individuals with chronic psychosis with type 2 diabetes mellitus, and patients with chronic psychosis without diabetes in order to determine if there were any differences in frequency of positive glutamic acid decarboxylase 65Ab or in mean values of glutamic acid decarboxylase 65Ab. The authors explain the theory behind their small study and why the sample size was likely too small to detect differences.

And finally, Meymandi advises us to be like Abu Ali Sina and Ibn al-Nadim and become addicted to reading. He explains why this is important to us as adults and to our children.
Amir Kalali, MD
Editor, Innovations in Clinical Neuroscience?