Mental Disorders

Negative Symptom Dimensions of the Positive and Negative Syndrome Scale Across Geographical Regions: Implications for Social, Linguistic, and Cultural Consistency
by Anzalee Khan, PhD; Lora Liharska, MS; Philip D. Harvey, PhD; Alexandra Atkins, PhD; Daniel Ulshen, BA; and Richard S.E. Keefe, PhD Dr. Khan is Senior Biostatistician at NeuroCog Trials and holds an appointment in the Psychopharmacology Research Program at the Nathan S. Kline Institute for Psychiatric Research in Orangeburg, New York. Ms. Liharska is […]

Disparity between General Symptom Relief and Remission Criteria in the Positive and Negative Syndrome Scale (PANSS): A Post-treatment Bifactor Item Response Theory Model
by Ariana E. Anderson, PhD; Steven P. Reise, PhD; Stephen R. Marder, MD; Maxwell Mansolf, MS; Carol Han, BS; and Robert M. Bilder, PhD Dr. Anderson is with the Department of Psychiatry and Biobehavioral Sciences and the Department of Statistics, Dr. Reise is with the Department of Psychology, Dr. Marder is with the Department of […]

Understanding Antipsychotic Drug Treatment Effects: A Novel Method to Reduce Pseudospecificity of the Positive and Negative Syndrome Scale (PANSS) Factors
by Seth C. Hopkins, PhD; Ajay Ogirala, PhD, Antony Loebel, MD; and Kenneth S. Koblan, PhD Drs. Hopkins, Ogirala, Loebel, and Koblan are with Sunovion Pharmaceuticals Inc, Marlborough, Massachusetts. Funding: Funding was provided by Sunovion Pharmaceuticals Inc. Disclosures: The authors are employees of Sunovion Pharmaceuticals Inc. Abtract: The Positive and Negative Syndrome Scale (PANSS) is the […]

Sensitivity of the Positive and Negative Syndrome Scale (PANSS) in Detecting Treatment Effects via Network Analysis
by Farnaz Zamani Esfahlani, MS; Hiroki Sayama, DSc; Katherine Frost Visser, MS; and Gregory P. Strauss, PhD Ms. Zamani Esfahlani is a PhD candidate in the Systems Science program at the State University of New York at Binghamton. Dr. Sayama is the director of the Center for Collective Dynamics of Complex Systems (CoCo), professor in […]

Are Shorter Versions of the Positive and Negative Syndrome Scale (PANSS) Doable? A Critical Review
by Jean-Pierre Lindenmayer, MD Dr. Lindenmayer is Clinical Professor of the Department of Psychiatry at the NYU School of Medicine in New York, New York. Funding: No funding was provided for this article. Disclosures: The author has no financial conflicts relevant to the content of this article. Abstract: The Positive and Negative Syndrome Scale (PANSS) […]

Positive and Negative Syndrome Scale (PANSS) Training: Challenges, Solutions, and Future Directions
by Mark G. A. Opler, PhD, MPH; Christian Yavorsky, PhD; and David G Daniel, MD Dr. Opler is Adjunct Assistant Professor at NYU School of Medicine and Chief Research Officer at MedAvante-ProPhase Inc. in New York, New York. Dr. Yavorsky is Chief Scientific Officer and Clinical Director at Cronos Clinical Consulting in Lambertville, New Jersey. Dr. […]

Differential Diagnoses: Encephalopathy or Psychosis?
by Malathi Latha Perugula, MD, and Steven Lippmann, MD The authors are from the Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, Louisville, Kentucky. Innov Clin Neurosci. 2016;13(11–12):41–42. This column series compares neurological conditions that pose differential challenges in diagnoses. Funding: No funding was provided for the preparation of this article. […]

Differential Diagnoses: Delirium or Dementia?
by Steven Lippmann, MD, and Malathi Latha Perugula, MD The authors are from the Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, Louisville, Kentucky. Innov Clin Neurosci. 2016;13(9–10):56–57. This column series compares neurological conditions that pose differential challenges in diagnoses. Funding: No funding was provided for the preparation of this article. […]

The Neuroscience Report—Vol. 45 (September 15, 2016): Schizophrenia
The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]
Bridging the Measurement Gap Between Research and Clinical Care in Schizophrenia: Positive and Negative Syndrome Scale-6 (PANSS-6) and Other Assessments Based on the Simplified Negative and Positive Symptoms Interview (SNAPSI)
by Søren D. Østergaard, MD, PhD; Mark G. A. Opler, PhD, MPh; and Christoph U. Correll, MD Dr. Østergaard is Associate Professor at Aarhus University in Denmark. Dr. Opler is Adjunct Assistant Professor at NYU School of Medicine and Chief Research Officer at MedAvante-ProPhase, Inc. Dr. Correll is Medical Director of the Recognition and Prevention program […]
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