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Effects of Lisdexamfetamine Dimesylate on Functional Impairment Measured on the Sheehan Disability Scale in Adults With Moderate-to-severe Binge Eating Disorder: Results from Two Randomized, Placebo-controlled Trials

by David V. Sheehan, MD, MBA; Maria Gasior, MD, PhD; Susan L. McElroy, MD; Jana Radewonuk, MSc; Barry K. Herman, MD, MMM; and James Hudson, MD, ScD Dr. Sheehan is

Combination Phentermine–Topiramate Extended Release for the Treatment of Binge Eating Disorder: An Open-Label, Prospective Study

By Anna I. Guerdjikova, PhD, LISW; Stephanie Williams, MS; Thomas J. Blom, MS; Nicole Mori, CNP; and Susan L. McElroy, MD Drs. Guerdjikova and McElroy and Ms. Mori are with

Valbenazine and Deutetrabenazine for Tardive Dyskinesia

By Katie T. B. Touma, PharmD, BCPP, BCPS, and Jonathan R. Scarff, MD Dr. Touma is with the William Jennings Bryan Dorn VA Medical Center Community-based Outpatient Clinic in Anderson,

Risk Management: Lessons to Be Learned: A Review of Post-suicide Malpractice Lawsuits

By Ann Mcnary, JD Ms. McNary is Senior Risk Manager at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: Ms. McNary

Letter to the Editor: Kratom and the Opioid Crisis

Innov Clin Neurosci. 2018;15(5–6):11–12 Dr. Bestha is with the Carolinas Healthcare System in Charlotte, North Carolina. Funding/financial disclosures. The author has no conflicts of interest relevant to the content of

Editorial Message and Issue Highlights–Vol. 15, No. 3–4, March-April 2018

Dear Colleagues: Welcome to the March–April 2018 issue of Innovations in Clinical Neuroscience (ICNS). We are excited to lead this edition of ICNS with an exciting commentary by Dr. Michael

Neuroscience is the Next Oncology

by Michael D. Ehlers, MD, PhD Dr. Ehlers is with Biogen in Cambridge, Massachusetts. Innov Clin Neurosci. 2018;15(3–4):15–16 Funding: No funding was received for the preparation of this article. Disclosures:

Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury

by Amne Borghol, PharmD, BCPS, BCGP; Michael Aucoin, PharmD; Ifeanyichukwu Onor, PharmD, BCPS; Dana Jamero, PharmD, BCOP; and Fadi Hawawini, DO, CMD Drs. Borghol, Onor, and Jamero are with the

Effects of Statins and Cholesterol on Patient Aggression: Is There a Connection?

by Emily Leppien, PharmD, BCPS; Kimberly Mulcahy, PharmD, BCPS, BCPP; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; Eileen Trigoboff, RN, PMHCNS-BC, DNS, DABFN; and Lewis Opler, MD, PhD† Drs.

Comorbid Insomnia and Psychiatric Disorders: An Update

by Khurshid A. Khurshid, MD, FAASM Dr. Khurshid is Clinical Associate Profressor and Chief of the Neuromodulation and Sleep Disorders Program in the Department of Psychiatry at the University of

Psychosis in a Child with Atypical Autism: A Case Report and a Brief Review of the Association of Psychosis and Autism

by Swapnajeet Sahoo, MD; Susanta Kumar Padhy, MD; Neha Singla, MD; and Aakanksha Singh, MD Drs. Sahoo, Singla, and Singh are Senior Residents and Dr. Padhy is Associate Professor in

Audio Recording for Independent Confirmation of Clinical Assessments in Generalized Anxiety Disorder

by Steven D. Targum, MD; Christopher Murphy, PhD; Jibran Khan, BA; Laura Zumpano, BA; Mark Whitlock, PhD; Arthur A. Simen, MD, PhD; and Brendon Binneman, MD† Drs. Targum and Murphy

Hot Topics in Neuroscience: Is Electroconvulsive Therapy a Treatment for Depression Following Traumatic Brain Injury?

This ongoing column explores off-label or emerging treatment options, drug development trends, and theoretical concepts in the field of neuroscience. by Anja Srienc, PhD, MD; Puneet Narang, MD; Simrat Sarai,

Risk Management: Prescribing Controlled Substances: Managing the Risks

by Donna Vanderpool, MBA, JD Ms. Vanderpool is Vice President, Risk Management at PRMS, Inc. in Arlington, Virginia. Innov Clin Neurosci. 2018;15(3–4):47–51 Funding: No funding was provided for the preparation

Letter to the Editor: Discussing ANT1 role in Amyotrophic Lateral Sclerosis pathogenesis

Innov Clin Neurosci. 2018;15(3–4):11–14 Dear Editor: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a rapid progression, affecting motor neurons in the brain and spinal cord, ultimately leading to

Letter to the Editor: Olanzapine and Diabetic Ketoacidosis: What is the Underlying Mechanism?

Innov Clin Neurosci. 2018;15(3–4):11–14 Dear Editor: Recently, Iwaku et al1 reported a detailed case of olanzapine-related acute-onset Type 1 diabetes with ketoacidosis.1 They concluded that olanzapine sometimes can cause sudden

Letter to the Editor: Prolactin levels in Patients with Schizophrenia who were switched from daily to once-monthly Aripiprazole treatment

Innov Clin Neurosci. 2018;15(3–4):11–14 Dear Editor: Schizophrenia is a chronic and progressive psychiatric disorder requiring long-term treatment with antipsychotics. The use of long-acting injectable antipsychotics (LAI) has been shown to

Editorial Message and Issue Highlights–Vol. 15, No. 1–2, January-February 2018

Dear Colleagues: Welcome to the January-February 2018 issue of Innovations in Clinical Neuroscience (ICNS). This is a milestone year for us as it marks the beginning of our 15th year