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Letter to the Editor: Elevated Level of CXCL13 in Nonenhancing Diffuse Primary Lymphoma of the Brainstem

Letter to the Editor: Elevated Level of CXCL13 in Nonenhancing Diffuse Primary Lymphoma of the Brainstem

| October 1, 2021

Innov Clin Neurosci. 2021;18(10–12):8. Dear Editor: Primary central nervous system (CNS) lymphoma (pCNL) is a rare neoplasia predominantly of the brain. Histologically, most of these neoplasias are diffuse large B-cell lymphomas.1 Although the exact diagnosis requires pathological confirmation, magnetic resonance imaging (MRI) often shows characteristic results, such as enhancement.2 However, nonenhancing pCNL have been described […]

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Palmitoylethanolamide/Luteolin as Adjuvant Therapy to Improve an Unusual Case of Camptocormia in a Patient with Parkinson’s Disease:  A Case Report

Palmitoylethanolamide/Luteolin as Adjuvant Therapy to Improve an Unusual Case of Camptocormia in a Patient with Parkinson’s Disease: A Case Report

| October 1, 2021

by Stefania Brotini, MD Dr. Brotini is with the Movement Disorder Center, Department of Neurology, San Giuseppe Hospital in Empoli, Florence, Italy FUNDING: No funding was provided for this study.  DISCLOSURES: The author has no conflicts of interest relevant to the content of this article.  Innov Clin Neurosci. 2021;18(10–12):12–14. ABSTRACT: Background. Camptocormia is a complication in […]

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Clinician- and Patient-reported Endpoints in CNS Orphan Drug Clinical Trials: ISCTM Position Paper on Best Practices for Endpoint Selection, Validation, Training, and Standardization

Clinician- and Patient-reported Endpoints in CNS Orphan Drug Clinical Trials: ISCTM Position Paper on Best Practices for Endpoint Selection, Validation, Training, and Standardization

| October 1, 2021

by Joan Busner, PhD; Gahan Pandina, PhD; Silvia Zaragoza domingo PhD; Anna-Karin Berger PhD; Maria T. Acosta, MD; Nahome Fisseha, PharmD; Joseph Horrigan, MD; Jelena Ivkovic, MD; William Jacobson, PhD; Dennis Revicki, PhD; and Victoria Villalta-Gil, PhD, MSc All authors are members of the ISCTM Working Group for Rare Disease/Orphan Drug Development; Drs. Busner and Pandina […]

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Is Neuromuscular Electrical Stimulation Effective in Treating Severe Dysarthria: Insights from a Case Study

Is Neuromuscular Electrical Stimulation Effective in Treating Severe Dysarthria: Insights from a Case Study

| October 1, 2021

by Matteo Berenati, MSc; Antonino Naro, MD, PhD; Cinzia Calabrò, MSc; Michele Torrisi, PsyD; Salvatore Massimiliano Cardali, MD; and Rocco Salvatore Calabrò, MD, PhD Mr. Berenati, Ms. C. Calabrò, and Drs. Naro, Torrisi, and R. Calabrò are with IRCCS Centro Neurolesi “Bonino-Pulejo” in Messina, Italy. Dr. Cardali is with UOC Neurochirurgia, AOU Policlinico G Martino in […]

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Sexual Function and Disability in the Neurorehabilitation Setting: An Urgent Need for a Multidisciplinary Approach

Sexual Function and Disability in the Neurorehabilitation Setting: An Urgent Need for a Multidisciplinary Approach

| October 1, 2021

by Rocco Salvatore Calabrò, MD, PhD, and Alfredo Manuli, MSc Dr. Calabrò is with the IRCCS Centro Neurolesi “Bonino-Pulejo” in Messina, Italy. Mr. Manuli is with the Physical Medicine and Rehabilitation Unit, AOU Policlinico Universitario in Messina, Italy. FUNDING: No funding was provided for this study.  DISCLOSURES: The author has no conflicts of interest relevant […]

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Development of a Cognitive Ability Assessment Tool for a Pediatric School-aged Population

Development of a Cognitive Ability Assessment Tool for a Pediatric School-aged Population

| October 1, 2021

by Franco Di Cesare, MD; Leonardo Di Cesare; and Cristiana Di Carlo, MSc  Dr. F. Di Cesare, Mr. L. Di Cesare, and Ms. Di Carlo are with Leoben Research srl in Rome, Italy. FUNDING: This study was supported by Leoben Research.  DISCLOSURES: The authors are employed by Leoben Research.  Innov Clin Neurosci. 2021;18(10–12):30–37. ABSTRACT: Objective. […]

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Risk Management: Fact or Fiction

Risk Management: Fact or Fiction

| October 1, 2021

by Donna Vanderpool, MBA, JD Ms. Vanderpool is Director of Risk Management at Professional Risk Management Services (PRMS) FUNDING: No funding was provided for the preparation of this article. DISCLOSURES: The author is an employee of PRMS. PRMS manages a professional liability insurance program for psychiatrists. Innov Clin Neurosci. 2021;18(10–12):38–39. Questions 1. A clinician’s former […]

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