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Category: Trial Methodology

Interactive Voice Response and Text-based Self-report Versions of the Electronic Columbia-Suicide Severity Rating Scale Are Equivalent

by Chad Gwaltney, PhD; James C Mundt, PhD; John H. Greist, MD; Jean Paty, PhD; and Brian Tiplady, PhD Dr. Gwaltney is with Gwaltney Consulting, Westerly, Rhode Island (with ERT

Outcomes Assessment in Clinical Trials of Alzheimer’s Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs

by Holly Posner, MD, MS; Rosie Curiel, PsyD; Chris Edgar, PhD; Suzanne Hendrix, PhD; Enchi Liu, PhD; David A. Loewenstein, PhD; Glenn Morrison, MSc, PhD; Leslie Shinobu, PhD; Keith Wesnes,

Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer’s Disease Spectrum

by Philip D. Harvey, PhD; Stephanie Cosentino, PhD; Rosie Curiel, PhD; Terry E. Goldberg, PhD; Jeffrey Kaye, MD; David Loewenstein, PhD; Daniel Marson, PhD, JD; David Salmon, PhD; Keith Wesnes,

CNS Summit 2016 Abstracts of Poster Presentations

Innov Clin Neurosci. 2017;14(1–2)3–23. A MESSAGE FROM THE EDITOR Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased

Editor’s Message: September–October 2016 Issue Highlights

Dear Colleagues: Welcome to the September-October 2016 issue of Innovations in Clinical Neuroscience (ICNS). As the official journal of the CNS Summit, the International Society for CNS Drug Development (ISCDD),

Performance, Reliability, Usability, and Safety of the ID-Cap System for Ingestion Event Monitoring in Healthy Volunteers: A Pilot Study

by Glen P. Flores, PhD; Brian Peace, BS; Tony C. Carnes, PhD; Susan L. Baumgartner, PharmD, MBA; D. Eric Buffkin, Jr., MBA; Neil R. Euliano, PhD; and Larry N. Smith,

Assessment of Cognitive and Neurologic Recovery in Ischemic Stroke Drug Trials: Results from a Randomized, Double-blind, Placebo-controlled Study

by Franco Di Cesare, MD; Jessica Mancuso, PhD; Brian Silver, MD; and Peter T. Loudon, PhD Dr. Di Cesare is with Leoben Research Limited in Glasgow, UK; Dr. Mancuso is

The Standard for Clinicians’ Interview in Psychiatry (SCIP): A Clinician-administered Tool with Categorical, Dimensional, and Numeric Output— Conceptual Development, Design, and Description of the SCIP

by Ahmed Aboraya, MD, DrPh; Henry Nasrallah, MD; Srinivas Muvvala, MD, MPH; Ahmed El-Missiry, MD, MRCPsych, IFAPA; Hader Mansour, MD, PhD; Cheryl Hill, MD PhD; Daniel Elswick, MD; and Elizabeth

The Neuroscience Report—Vol. 41 (May 20, 2016): Human Brain vs. Artificial Intelligence

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to

Editor’s Message and Issue Highlights

Dear Colleagues: Welcome to the March–April 2016 issue of Innovations in Clinical Neuroscience (ICNS). Attitudes regarding marijuana use have changed dramatically over the past 50-plus years in the United States.

Inter-rater Reliability Assessment of ASPECT-R (A Study Pragmatic-Explanatory Characterization Tool-Rating)

by Cynthia A. Bossie, PhD; Larry D. Alphs, MD, PhD; David Williamson, PhD; Lian Mao, PhD; Clennon Kurut, BS; and the ASPECT-R Rater Team Drs. Bossie, Alphs, and Williamson are

The Neuroscience Report—Vol. 38 (March 22, 2016): Building Better Clinical Trials

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to

ASPECT-R—A Tool to Rate the Pragmatic and Explanatory Characteristics of a Clinical Trial Design

by Larry D. Alphs, MD, PhD, and Cynthia A. Bossie, PhD Drs. Alphs and Bossie are with Janssen Scientific Affairs, LLC, Titusville, New Jersey, USA. Innov Clin Neurosci. 2016;13(1–2):15–26. Funding:

Data Quality Monitoring in Clinical Trials: Has It Been Worth It? An Evaluation and Prediction of the Future by All Stakeholders

by the CNS SUMMIT DATA QUALITY MONITORING WORKGROUP CORE MEMBERS—David Daniel, MD; Amir Kalali, MD; Mark West; David Walling, PhD; Dana Hilt, MD; Nina Engelhardt, PhD; Larry Alphs, MD, PhD;

The Neuroscience Report—Vol. 34 (January 25, 2016): Patient Adherence

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to

Supplement to November–December 2015 Issue: Abstracts of Poster Presentations: CNS Summit 2015

October 7–11, 2015 Boca Raton, Florida Innov Clin Neurosci. 2015;12(11–12 Suppl C):3–17. CNS Drug Compounds Synthesis of carnitine analogues for inhibition of carnitine palmitoyltransferase Presenters: Bornstein J, Garneau-Tsodikova S Affiliations:

The Neuroscience Report—Vol. 25 (October 18, 2015): Duplicate Patients in Clinical Trials

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to