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Editorial Message and Issue Highlights–Vol. 18, No. 1–3, January–March 2021

Dear Colleagues: Welcome to the January–March 2021 edition of Innovations in Clinical Neuroscience (ICNS). For 2021’s first quarterly issue of ICNS, we start with two letters to the editor. In

Longitudinal Data in Patients with Niemann-Pick Type C Disease Under Combined High Intrathecal and Low Intravenous Dose of 2-hydroxylpropyl-β-cyclodextrin

by Evangelia Bountouvi, MD, PhD; Melpomeni Giorgi, MD; Anna Papadopoulou, PhD; Kaj Blennow, PhD; Ingemar Björkhem, PhD; Maria Tsirouda, PhD; Spyridon Kanellakis, Msc, PhD; Andreas Fryganas, MD; Maria Spanou, MD;

Catatonia in a 6-year-old Patient Following Disseminated Group A Streptococcus Infection

by Philip B Cawkwell, MD; Ivan Daniel Mayor, BA; and Richard J. Shaw,MD Drs. Cawkwell and Shaw and Mr. Mayor are with the Department of Psychiatry and Behavioral Sciences, Division

Blood–Brain Barrier: COVID-19, Pandemics, and Cytokine Norms

by Atmaram Yarlagadda, MD; Samuel L. Preston, DO; Rachel P. Jeyadhas, MD; Adam Edward Lang, PharmD; Rasha Hammamieh, PhD; And Anita H. Clayton, MD Dr. Yarlagadda is the Installation Director