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Category: Past Articles

Pimavanserin in the Treatment of Parkinson’s Disease Psychosis: Meta-analysis and Meta-regression of Randomized Clinical Trials

by Zeeshan Mansuri, MD, MPH; Abhishek Reddy, MD; Ramu Vadukapuram, MD; Chintan Trivedi, MD, MPH; and Amy Amara, MD, PhD Dr. Mansuri is with the Department of Psychiatry, Boston Children’s

Using Artificial Intelligence-based Methods to Address the Placebo Response in Clinical Trials

by Erica A. Smith, PhD; William P. Horan, PhD; Dominique Demolle, PhD; Peter Schueler, MD; Dong-Jing Fu, MD, PhD; Ariana E. Anderson, PhD; Joseph Geraci, MSc, PhD; Florence Butlen-Ducuing, MD,

Risk Management: Responding to Record Requests: The Basics

by Ann L. McNary, JD Ms. McNary is Senior Risk Manager at Professional Risk Management Services (PRMS) Funding: No funding was provided for the preparation of this article. Disclosures: The

Letter to the Editor: Elevated Level of CXCL13 in Nonenhancing Diffuse Primary Lymphoma of the Brainstem

Innov Clin Neurosci. 2021;18(10–12):8. Dear Editor: Primary central nervous system (CNS) lymphoma (pCNL) is a rare neoplasia predominantly of the brain. Histologically, most of these neoplasias are diffuse large B-cell

Palmitoylethanolamide/Luteolin as Adjuvant Therapy to Improve an Unusual Case of Camptocormia in a Patient with Parkinson’s Disease: A Case Report

by Stefania Brotini, MD Dr. Brotini is with the Movement Disorder Center, Department of Neurology, San Giuseppe Hospital in Empoli, Florence, Italy FUNDING: No funding was provided for this study.

Clinician- and Patient-reported Endpoints in CNS Orphan Drug Clinical Trials: ISCTM Position Paper on Best Practices for Endpoint Selection, Validation, Training, and Standardization

by Joan Busner, PhD; Gahan Pandina, PhD; Silvia Zaragoza domingo PhD; Anna-Karin Berger PhD; Maria T. Acosta, MD; Nahome Fisseha, PharmD; Joseph Horrigan, MD; Jelena Ivkovic, MD; William Jacobson, PhD;

Is Neuromuscular Electrical Stimulation Effective in Treating Severe Dysarthria: Insights from a Case Study

by Matteo Berenati, MSc; Antonino Naro, MD, PhD; Cinzia Calabrò, MSc; Michele Torrisi, PsyD; Salvatore Massimiliano Cardali, MD; and Rocco Salvatore Calabrò, MD, PhD Mr. Berenati, Ms. C. Calabrò, and

Sexual Function and Disability in the Neurorehabilitation Setting: An Urgent Need for a Multidisciplinary Approach

by Rocco Salvatore Calabrò, MD, PhD, and Alfredo Manuli, MSc Dr. Calabrò is with the IRCCS Centro Neurolesi “Bonino-Pulejo” in Messina, Italy. Mr. Manuli is with the Physical Medicine and

Development of a Cognitive Ability Assessment Tool for a Pediatric School-aged Population

by Franco Di Cesare, MD; Leonardo Di Cesare; and Cristiana Di Carlo, MSc Dr. F. Di Cesare, Mr. L. Di Cesare, and Ms. Di Carlo are with Leoben Research srl

Risk Management: Fact or Fiction

by Donna Vanderpool, MBA, JD Ms. Vanderpool is Director of Risk Management at Professional Risk Management Services (PRMS) FUNDING: No funding was provided for the preparation of this article. DISCLOSURES:

Letter to the Editor: Beyond Robotics and Virtual Reality: It’s Time to go Back to the Patient!

Dear Editor: There is great scientific activity regarding robotics, virtual reality (VR), telehealth, and digital medicine.1–2 A “mischievous” point of view could tell that they are running after the real

Letter to the Editor: Beware of Neuroleptic Malignant Syndrome in COVID-19 Pandemic

Dear Editor: I read with great interest the recent article by Buttar et al1 detailing fatal consequences of the chronic neuroleptic malignant syndrome (NMS) from the United States. The authors

Letter to the Editor: Adjunct Ketamine in Electroconvulsive Therapy

Dear Editor: Electroconvulsive therapy (ECT) is a medical treatment that involves the electrical stimulation of the brain under general anesthesia. This treatment modality has been utilized worldwide for over 80

Facial Diplegia with Preserved Reflexes: An Unusual Case of Anti-GD1b Antibody Associated Guillain-Barré Syndrome

by Riwaj Bhagat, MD, and Martin Brown, MD Dr. Bhagat and Dr. Brown are with the University of Louisville, Department of Neurology in Louisville, Kentucky. FUNDING: No funding was provided