Trial Methodology

Adult Neurogenesis in Humans: A Review of Basic Concepts, History, Current Research, and Clinical Implications
by Ashutosh Kumar, MD; Vikas Pareek, PhD; Muneeb A. Faiq, PhD; Sanjib K. Ghosh, MD; and Chiman Kumari, MD Drs. Kumar and Ghosh are with the Department of Anatomy at the All India Institute of Medical Sciences (AIIMS) in Patna, India. Dr. Pareek is with the Computational Neuroscience and Neuroimaging Division at National Brain Research […]

Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis
by Laetitia Pouzol, MSc, PharmD; Luca Piali, PhD; Claude CA Bernard, PhD; Marianne M. Martinic, PhD; Beat Steiner, PhD; and Martine Clozel, MD Drs. Pouzol and Clozel were with Actelion Pharmaceuticals Ltd. in Allschwil, Switzerland, at the time of this research, and are presently with Idorsia Pharmaceuticals Ltd. in Allschwil, Switzerland. Dr. Piali was with […]

CNS Summit 2018 Abstracts of Poster Presentations
A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that is being presented during CNS Summit 2018. The supplement is also available online by visiting […]

Validation of an Equation Model to Predict Intracranial Pressure in Clinical Studies
by Niro Kasahara, MD; Mateus L. Matuoka, MD; Katia S. Santos, MD; Natasha F.S. Cruz, MD; Alvaro R. Martins, MD; and Stanley Nigro, MD Drs. Kasahara, Matuoka, Santos, and Cruz are with the Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo in Sao Paulo, Brazil. Dr. Kasahara is also with Santa […]

The Assessment and Measurement of Wellness in the Clinical Medical Setting: A Systematic Review
by Ryan Bart, DO; Waguih William IsHak, MD, FAPA; Shaina Ganjian, MS; Karim Yahia Jaffer; Marina Abdelmesseh, MD, CIC; Sophia Hanna, BA; Yasmine Gohar, BA; Gezelle Azar, Bs; Brigitte Vanle, PhD; Jonathan Dang, MD; and Itai Danovitch, MD Dr. Bart is with Western University of Health Sciences and Cedars-Sinai Medical Center, in Los Angeles, California. […]

Validation of the Russian Version of the Positive and Negative Syndrome Scale (PANSS-Ru) and Normative Data
by Evgenia Ivanova, PhD; Anzalee Khan, PhD; Lora Liharska, MS; Alexander Reznik, MD, PhD; Sergey Kuzmin, MD; Olga Kushnir, MD, PhD; Alexey Agarkov, MD, PhD; Nikolay Bokhan, MD, PhD; Tatiana Pogorelova, MD, PhD; Olga Khomenko, MD; Ksenia Chernysheva, MD, PhD; Margarita Morozova, MD, PhD; George Rupchev, PhD; Taisia Lepilkina, PhD; Alexander Ozornin, MD, PhD; Nina […]

Implementation of the Electronic Columbia-Suicide Severity Rating Scale (eC-SSRS™) Across Four Phase IIIB Clinical Trials in HIV-Infected Individuals (ARIA, STRIIVING, DAWNING and INSPIRING)
By Clare Brennan, DPT, MSPH; Hannah Whillis, MS; Choy Man, BS; Brian Wynne, MD; Vani Vannappagari, MBBS, MPH, PhD Dr. Brennan and and Ms. Man are with Clinical Development and Dr. Vannappagari is with Epidemiology and Real World Evidence at ViiV Healthcare in Research Triangle Park, North Carolina. Ms. Whillis was with GlaxoSmithKline, plc, in […]

Letter to the Editor: Can YouTube® Disseminate Dementia Knowledge to Sinagpore Chinese?
By Benjamin K.P. Woo, MD Funding/financial disclosures: The authors have no conflicts of interest relevant to the content of this letter. No funding was received for the preparation of this letter. Dear Editor: A community-based epidemiological survey has suggested that the prevalence of cognitive impairment and dementia is approximately 15.2 percent in Singapore Chinese.[1] While early […]