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Impact of COVID-19 Pandemic on Patients with Serious Mental Illness (SMI) and Nonpsychiatric Control Subjects in Clinical Trials

by Maria Fe Garcia-Rada, MPS, and Robert E. Litman, MD Ms. Fe Garcia-Rada and Dr. Litman are with CenExel CBH Health in Gaithersburg, Maryland. Dr. Litman is additionally with Georgetown

Current and Emerging Technologies to Address the Placebo Response Challenge in CNS Clinical Trials: Promise, Pitfalls, and Pathways Forward

by William P. Horan, PhD; Gary Sachs, MD; Dawn I. Velligan, PhD; Michael Davis, MD, PhD; Richard S.E. Keefe, PhD; Ni A. Khin, MD; Florence Butlen-Ducuing, MD, PhD; and Philip

Ensuring Stakeholder Feedback in the Design and Conduct of Clinical Trials for Rare Diseases: ISCTM Position Paper of the Orphan Disease Working Group

by Gahan J. Pandina, PhD; Joan Busner, PhD; Lucas Kempf, MD; Joan Fallon, BS, DC; Larry D. Alphs, MD, PhD; Maria T. Acosta, MD; Anna-Karin Berger, PhD; Simon Day, PhD;

WORDS: A New Verbal Memory Test to Evaluate Cognitive Health in a Zambian School-aged Population

by Franco Di Cesare, MD; Giulia Piccinini, MD; Cristiana Di Carlo, MPhil; and Leonardo Di Cesare, MD Drs. F. Di Cesare, Di Carlo, and L. Di Cesare are with Leoben

Innovative Technologies in CNS Trials: Promises and Pitfalls for Recruitment, Retention, and Representativeness

by Jacqueline Lutz, PhD; Abhishek Pratap, PhD; Eric J. Lenze, MD; Durga Bestha, MD; Jessica M. Lipschitz, PhD; Stella Karantzoulis, PhD; Uma Vaidyanathan, PhD; Jessica Robin, PhD; William Horan, PhD;

WAVES: A Novel Test to Evaluate Visuospatial Construction Ability in a School-aged Population

by Franco Di Cesare, MD; Cristiana Di Carlo, MSc; and Leonardo Di Cesare, MD Drs. F. Di Cesare and Di Carlo are with Leoben Research srl in Rome, Italy. Dr.

Development of a Symbol Cancellation Test to Evaluate Attention in a School-aged Zambian Population

by Franco Di Cesare, MD; Cristiana Di Carlo, MSc; and Leonardo Di Cesare, MD Drs. F. Di Cesare and Di Carlo are with Leoben Research srl in Rome, Italy. Dr.

Impact of COVID-19 Pandemic on Psychiatric Patients at Clinical Trial Sites

by Maria Fe Garcia-Rada, MPS, and Robert E. Litman, MD Ms. Garcia-Rada and Dr. Litman are with CenExel CBH Health in Gaithersburg, Maryland. Dr. Litman is with Georgetown University Medical

CNS Summit 2022 Abstracts of Poster Presentations

A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with

Implementing Digital Technologies in Clinical Trials: Lessons Learned

by Georgia Mitsi, PhD; Todd Grinnell, BA; Suzanne Giordano, PhD; Thomas Goodin, Phd; Shahin Sanjar, PhD; Elizabeth Marble, BS; and Andrei Pikalov, MD, PhD All authors are with Sunovion Pharmaceuticals

Using Artificial Intelligence-based Methods to Address the Placebo Response in Clinical Trials

by Erica A. Smith, PhD; William P. Horan, PhD; Dominique Demolle, PhD; Peter Schueler, MD; Dong-Jing Fu, MD, PhD; Ariana E. Anderson, PhD; Joseph Geraci, MSc, PhD; Florence Butlen-Ducuing, MD,

CNS Summit 2021 Abstracts of Poster Presentations

A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with

CNS Summit 2020 Abstracts of Poster Presentations

A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with

Drug Development for Mental Illness: How Psychiatry Clinical Trial Sites are Meeting the Challenge of the COVID-19 Pandemic

by Robert E. Litman, MD; Peter Sorantin, PhD; and Elia E. Acevedo-Diaz, MD Drs. Litman is with CBH Health, Georgetown University Medical School in Washington, DC. Dr. Sorantin is with

CNS Summit 2019 Abstracts of Poster Presentations

A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with

Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies

by Mark E. Whitlock, PhD; Philip W. Woodward, MPhil; and Robert C. Alexander, MD Dr. Whitlock is BioStatistics Head of Internal Medicine, Early Clinical Development, for Pfizer in Cambridge, United

CNS Summit 2018 Abstracts of Poster Presentations

A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with