Tag: clinical trials
Implementing Digital Technologies in Clinical Trials: Lessons Learned
by Georgia Mitsi, PhD; Todd Grinnell, BA; Suzanne Giordano, PhD; Thomas Goodin, Phd; Shahin Sanjar, PhD; Elizabeth Marble, BS; and Andrei Pikalov, MD, PhD All authors are with Sunovion Pharmaceuticals Inc. in Marlborough, Massachusetts. Funding: The studies described herein and medical writing support were supported by funding from Sunovion Pharmaceuticals Inc. Disclosures: All authors […]
Using Artificial Intelligence-based Methods to Address the Placebo Response in Clinical Trials
by Erica A. Smith, PhD; William P. Horan, PhD; Dominique Demolle, PhD; Peter Schueler, MD; Dong-Jing Fu, MD, PhD; Ariana E. Anderson, PhD; Joseph Geraci, MSc, PhD; Florence Butlen-Ducuing, MD, PhD; Jasmine Link, MS; Ni A. Khin, MD; Robert Morlock, PhD; and Larry D. Alphs, MD, PhD Drs. Smith and Demolle are with Cognivia in Mont St. […]
CNS Summit 2021 Abstracts of Poster Presentations
A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research presented during the CNS Summit 2021 event. The supplement is also available online by visiting www.innovationscns.com. […]
CNS Summit 2020 Abstracts of Poster Presentations
A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that was presented during the CNS Summit 2020 event. The supplement is also available online by […]
CNS Summit 2019 Abstracts of Poster Presentations
A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that is being presented during CNS Summit 2019. The supplement is also available online by visiting […]
Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies
by Mark E. Whitlock, PhD; Philip W. Woodward, MPhil; and Robert C. Alexander, MD Dr. Whitlock is BioStatistics Head of Internal Medicine, Early Clinical Development, for Pfizer in Cambridge, United Kingdom. Mr. Woodward is an independent statistics consultant in Newmarket, United Kingdom. Dr. Alexander is with Takeda Pharmaceuticals International Company in Cambridge, Massachusetts. Funding: No […]
CNS Summit 2018 Abstracts of Poster Presentations
A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that is being presented during CNS Summit 2018. The supplement is also available online by visiting […]
The 30th Anniversary of PANSS Special Edition
Dear Colleagues: Thirty years ago, the Positive and Negative Syndrome Scale (PANSS) was developed and published by Stanley Kay, Abraham Fiszbein, and Lewis Opler to identify the presence and severity of psychopathology symptoms in patients with psychotic disorders, with the objective of measuring patient characteristics and evaluating change over time using 30 symptoms rated on […]
Understanding Antipsychotic Drug Treatment Effects: A Novel Method to Reduce Pseudospecificity of the Positive and Negative Syndrome Scale (PANSS) Factors
by Seth C. Hopkins, PhD; Ajay Ogirala, PhD, Antony Loebel, MD; and Kenneth S. Koblan, PhD Drs. Hopkins, Ogirala, Loebel, and Koblan are with Sunovion Pharmaceuticals Inc, Marlborough, Massachusetts. Funding: Funding was provided by Sunovion Pharmaceuticals Inc. Disclosures: The authors are employees of Sunovion Pharmaceuticals Inc. Abtract: The Positive and Negative Syndrome Scale (PANSS) is the […]
Drug Development for Mental Illness: How Psychiatry Clinical Trial Sites are Meeting the Challenge of the COVID-19 Pandemic
by Robert E. Litman, MD; Peter Sorantin, PhD; and Elia E. Acevedo-Diaz, MD Drs. Litman is with CBH Health, Georgetown University Medical School in Washington, DC. Dr. Sorantin is with Sorantin Outcomes, LLC, in Mountain Lakes, New Jersey. Dr. Acevedo-Diaz is with CBH Health and the National Institute of Mental Health (NIMH) in Bethesda, Maryland. […]
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