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Clinician- and Patient-reported Endpoints in CNS Orphan Drug Clinical Trials: ISCTM Position Paper on Best Practices for Endpoint Selection, Validation, Training, and Standardization

by Joan Busner, PhD; Gahan Pandina, PhD; Silvia Zaragoza domingo PhD; Anna-Karin Berger PhD; Maria T. Acosta, MD; Nahome Fisseha, PharmD; Joseph Horrigan, MD; Jelena Ivkovic, MD; William Jacobson, PhD;

Is Neuromuscular Electrical Stimulation Effective in Treating Severe Dysarthria: Insights from a Case Study

by Matteo Berenati, MSc; Antonino Naro, MD, PhD; Cinzia Calabrò, MSc; Michele Torrisi, PsyD; Salvatore Massimiliano Cardali, MD; and Rocco Salvatore Calabrò, MD, PhD Mr. Berenati, Ms. C. Calabrò, and

Sexual Function and Disability in the Neurorehabilitation Setting: An Urgent Need for a Multidisciplinary Approach

by Rocco Salvatore Calabrò, MD, PhD, and Alfredo Manuli, MSc Dr. Calabrò is with the IRCCS Centro Neurolesi “Bonino-Pulejo” in Messina, Italy. Mr. Manuli is with the Physical Medicine and

Development of a Cognitive Ability Assessment Tool for a Pediatric School-aged Population

by Franco Di Cesare, MD; Leonardo Di Cesare; and Cristiana Di Carlo, MSc Dr. F. Di Cesare, Mr. L. Di Cesare, and Ms. Di Carlo are with Leoben Research srl

Risk Management: Fact or Fiction

by Donna Vanderpool, MBA, JD Ms. Vanderpool is Director of Risk Management at Professional Risk Management Services (PRMS) FUNDING: No funding was provided for the preparation of this article. DISCLOSURES:

CNS Summit 2021 Abstracts of Poster Presentations

A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with

Letter to the Editor: Beyond Robotics and Virtual Reality: It’s Time to go Back to the Patient!

Dear Editor: There is great scientific activity regarding robotics, virtual reality (VR), telehealth, and digital medicine.1–2 A “mischievous” point of view could tell that they are running after the real

Letter to the Editor: Beware of Neuroleptic Malignant Syndrome in COVID-19 Pandemic

Dear Editor: I read with great interest the recent article by Buttar et al1 detailing fatal consequences of the chronic neuroleptic malignant syndrome (NMS) from the United States. The authors

Letter to the Editor: Adjunct Ketamine in Electroconvulsive Therapy

Dear Editor: Electroconvulsive therapy (ECT) is a medical treatment that involves the electrical stimulation of the brain under general anesthesia. This treatment modality has been utilized worldwide for over 80

Cerebellar Atrophy Associated with Primary Sjögren’s Syndrome: Diagnosis, Therapy, and Virtual Reality Rehabilitation: A Case Report

by Emanuele Lo Voi, PhD; Giorgio Carmelo Basile, MD; Alessia Bramanti, PhD; Giuseppe Paladina, Annalisa Militi, MD; Daniele Bruschetta, MD; Angelo Alito,MD; Filippo Cavallaro; Salvatore Bertino, MD; and Demetrio Milardi,

Facial Diplegia with Preserved Reflexes: An Unusual Case of Anti-GD1b Antibody Associated Guillain-Barré Syndrome

by Riwaj Bhagat, MD, and Martin Brown, MD Dr. Bhagat and Dr. Brown are with the University of Louisville, Department of Neurology in Louisville, Kentucky. FUNDING: No funding was provided

Trends of Adverse Drug Reaction Reports in a Hospitalized Psychiatric Population: Exploring Prescriber Discontinuations as Potential Unreported Adverse Drug Events

by Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP, and Charisse Chehovich, PharmD Drs. Demler and Chehovich are with the Buffalo Psychiatric Center, New York State Office of Mental Health,

Acute Disseminated Encephalomyelitis: Psychiatric Presentation of a Rare Diagnosis

by Ashok Baral, MBBS; Rajan Gyawali, MBBS; Dikshya Upreti, MBBS; Atindra Mishra, MD; and Anoop Krishna Gupta, MD Ashok Baral, Rajan Gyawali, Dr. Upreti, and Dr. Gupta are with the

Risk Management: The Standard of Care

by Donna Vanderpool, MBA, JD Ms. Vanderpool is Director of Risk Management at Professional Risk Management Services (PRMS) FUNDING: No funding was provided for the preparation of this article. DISCLOSURES:

CNS Summit 2020 Abstracts of Poster Presentations

A message from the editor Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with