Innovations in Clinical Neuroscience

 

Providing evidence-based information in a practical, easy-to-read format for practicing clinicians, investigators, industry scientists, and other entities involved in the field of neuroscience

CNS Summit 2017

VOLUME 14, ISSUE 3–4, MARCH–APRIL 2017

Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Editor’s Message—Issue Highlights, March–April 2017

Editor’s Message—Issue Highlights, March–April 2017

Dear Colleagues: Welcome to the March–April 2017 issue of Innovations in Clinical Neuroscience. We start this issue with an interesting case series by Shroff titled, “Human Embryonic Stem Cells in the Treatment of Autism: A Case Series.” Here, investigators administered human embryonic stem cell therapy to three children with autism spectrum disorder (ASD) in an […]

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Human Embryonic Stem Cells in the Treatment of Autism:  A Case Series

Human Embryonic Stem Cells in the Treatment of Autism: A Case Series

by Geeta Shroff, MD Dr. Shroff is Director of Nutech Mediworld in New Delhi, India. Innov Clin Neurosci. 2017;14(3–4):12–16 Funding: No funding was received for the preparation of this article. Financial disclosures: The author has no conflicts of interest relevant to the content of this article. Key words: Autism, human embryonic stem cell, hESC, stem […]

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Interactive Voice Response and Text-based Self-report Versions of the Electronic Columbia-Suicide Severity Rating Scale Are Equivalent

Interactive Voice Response and Text-based Self-report Versions of the Electronic Columbia-Suicide Severity Rating Scale Are Equivalent

by Chad Gwaltney, PhD; James C Mundt, PhD; John H. Greist, MD; Jean Paty, PhD; and Brian Tiplady, PhD  Dr. Gwaltney is with Gwaltney Consulting, Westerly, Rhode Island (with ERT Inc. during the time of this study); Dr. Mundt is with ePRO Research Consulting, LLC, Sauk City, Wisconsin; Dr. Greist is Professor Emeritus of Psychiatry, University […]

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Liothyronine for Depression:  A Review and Guidance for Safety Monitoring

Liothyronine for Depression: A Review and Guidance for Safety Monitoring

by Katie T.B. Touma, PharmD, BCPP, BCPS; Allysa M. Zoucha, PharmD, BCPP; and Jonathan R. Scarff, MD Drs. Blissit and Zoucha are with William Jennings Bryan Dorn VA Medical Center, Anderson Community Based Outpatient Clinic, Anderson, South Carolina, and Dr. Scarff is with William Jennings Bryan Dorn VA Medical Center, Spartanburg Community Based Outpatient Clinic, […]

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Neuroendocrine, Autonomic, and Metabolic Responses to an Orexin Antagonist,  Suvorexant, in Psychiatric Patients with Insomnia

Neuroendocrine, Autonomic, and Metabolic Responses to an Orexin Antagonist, Suvorexant, in Psychiatric Patients with Insomnia

by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine, Kosekai-Kusatsu Hospital, in Hiroshima, Japan, and Dr. Nagamine is with the Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, in Yamaguchi, Japan. Innov Clin Neurosci. 2017;14(3–4):30–37 Funding: No funding was received for the preparation […]

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PAST ARTICLES (user login required)

CNS Summit 2016 Abstracts of Poster Presentations

CNS Summit 2016 Abstracts of Poster Presentations

Innov Clin Neurosci. 2017;14(1–2)3–23 A MESSAGE FROM THE EDITOR Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that was presented during CNS Summit 2016, which was held October 27 […]

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Editor’s Message: Issue Highlights, January–February 2017

Editor’s Message: Issue Highlights, January–February 2017

Dear Colleagues: Welcome to the January–February 2017 issue of Innovations in Clinical Neuroscience. We start our 14th year of publication strong with an interesting and diverse issue we hope you enjoy as much as we did putting it together. In the review article by Dascal et al, “Virtual Reality and Medical Inpatients: A Systematic Review […]

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Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials

Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials

by Julieta Dascal, BA; Mark Reid, PhD; Waguih William Ishak, MD, FAPA; Brennan Spiegel, MD, FACG; Jennifer Recacho, MA; Bradley Rosen, MD; and Itai Danovitch, MD, MBA All authors are from Cedars-Sinai Medical Center, Department of Psychiatry and Behavioral Neurosciences in Los Angeles, California. Innov Clin Neurosci. 2017;14(1–2):14–21 Funding: No funding was received for the […]

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Outcomes Assessment in Clinical Trials of Alzheimer’s Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs

Outcomes Assessment in Clinical Trials of Alzheimer’s Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs

by Holly Posner, MD, MS; Rosie Curiel, PsyD; Chris Edgar, PhD; Suzanne Hendrix, PhD; Enchi Liu, PhD; David A. Loewenstein, PhD; Glenn Morrison, MSc, PhD; Leslie Shinobu, PhD; Keith Wesnes, BSc, PhD, FSS, CPsychol, FBPsS; and Philip D. Harvey, PhD Dr. Posner is with Pfizer Inc., New York, New York; Drs. Curiel, Loewenstein, and Harvey […]

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Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer’s Disease Spectrum

Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer’s Disease Spectrum

by Philip D. Harvey, PhD; Stephanie Cosentino, PhD; Rosie Curiel, PhD; Terry E. Goldberg, PhD; Jeffrey Kaye, MD; David Loewenstein, PhD; Daniel Marson, PhD, JD; David Salmon, PhD; Keith Wesnes, PhD; and Holly Posner, MD Drs. Harvey, Curiel, and Loewenstein are with the University of Miami Leonard Miller School of Medicine, Department of Psychiatry and Behavioral Sciences, Miami, Florida; […]

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Behavioral and Stereological Analysis of the Effects of Intermittent Feeding Diet on the Orally Administrated MDMA (“ecstasy”) in Mice

Behavioral and Stereological Analysis of the Effects of Intermittent Feeding Diet on the Orally Administrated MDMA (“ecstasy”) in Mice

by Zeinab Ebrahimian, MSc; Zeinab Karimi, MSc; Mohammad Javad Khoshnoud, Pharm D, PhD; Mohammad Reza Namavar, PhD; Bahram Daraei, PharmD, PhD; and Moshen Raza Haidari, MD, PhD Drs. Ebrahimian and Khoshnoud are with the Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shiraz University of Medical Sciences in Shiraz, IR Iran; Drs. Karimi and Daraei […]

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THE NEUROSCIENCE REPORT

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information.   This […]

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The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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SPECIAL ISSUES AND SUPPLEMENTS

Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

CNS Summit 2016 Abstracts of Poster Presentations

CNS Summit 2016 Abstracts of Poster Presentations

Innov Clin Neurosci. 2017;14(1–2)3–23 A MESSAGE FROM THE EDITOR Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that was presented during CNS Summit 2016, which was held October 27 […]

Continue Reading

Hot Topics in Pain Management

Hot Topics in Pain Management

CLICK HERE TO ACCESS E-EDITION Past Issues                   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at […]

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Hot Topics in Drug Development

Hot Topics in Drug Development

Hot Topics in Drug Development PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Current Trends in Epilepsy Management

Current Trends in Epilepsy Management

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Supplement to Nov-Dec 2015 Issue: Abstracts of  Poster Presentations: CNS Summit 2015

Supplement to Nov-Dec 2015 Issue: Abstracts of Poster Presentations: CNS Summit 2015

October 7–11, 2015 Boca Raton, Florida Innov Clin Neurosci. 2015;12(11–12 Suppl C):3–17 CNS Drug Compounds Synthesis of carnitine analogues for inhibition of carnitine palmitoyltransferase Presenters: Bornstein J, Garneau-Tsodikova S Affiliations: University of Michigan Life Sciences Institute Background: Type 2 diabetes (T2DM) carries a markedly elevated risk of cerebrovascular disease. Carnitine plays a key role transporting […]

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Other Recent Posts

Current e-Edition

Current e-Edition

| April 1, 2017 | 0 Comments

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

Editor’s Message—Issue Highlights, March–April 2017

Editor’s Message—Issue Highlights, March–April 2017

| April 1, 2017 | 0 Comments

Dear Colleagues: Welcome to the March–April 2017 issue of Innovations in Clinical Neuroscience. We start this issue with an interesting case series by Shroff titled, “Human Embryonic Stem Cells in the Treatment of Autism: A Case Series.” Here, investigators administered human embryonic stem cell therapy to three children with autism spectrum disorder (ASD) in an […]

Continue Reading

Human Embryonic Stem Cells in the Treatment of Autism:  A Case Series

Human Embryonic Stem Cells in the Treatment of Autism: A Case Series

| April 1, 2017 | 0 Comments

by Geeta Shroff, MD Dr. Shroff is Director of Nutech Mediworld in New Delhi, India. Innov Clin Neurosci. 2017;14(3–4):12–16 Funding: No funding was received for the preparation of this article. Financial disclosures: The author has no conflicts of interest relevant to the content of this article. Key words: Autism, human embryonic stem cell, hESC, stem […]

Continue Reading

Interactive Voice Response and Text-based Self-report Versions of the Electronic Columbia-Suicide Severity Rating Scale Are Equivalent

Interactive Voice Response and Text-based Self-report Versions of the Electronic Columbia-Suicide Severity Rating Scale Are Equivalent

| April 1, 2017 | 0 Comments

by Chad Gwaltney, PhD; James C Mundt, PhD; John H. Greist, MD; Jean Paty, PhD; and Brian Tiplady, PhD  Dr. Gwaltney is with Gwaltney Consulting, Westerly, Rhode Island (with ERT Inc. during the time of this study); Dr. Mundt is with ePRO Research Consulting, LLC, Sauk City, Wisconsin; Dr. Greist is Professor Emeritus of Psychiatry, University […]

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Liothyronine for Depression:  A Review and Guidance for Safety Monitoring

Liothyronine for Depression: A Review and Guidance for Safety Monitoring

| April 1, 2017 | 0 Comments

by Katie T.B. Touma, PharmD, BCPP, BCPS; Allysa M. Zoucha, PharmD, BCPP; and Jonathan R. Scarff, MD Drs. Blissit and Zoucha are with William Jennings Bryan Dorn VA Medical Center, Anderson Community Based Outpatient Clinic, Anderson, South Carolina, and Dr. Scarff is with William Jennings Bryan Dorn VA Medical Center, Spartanburg Community Based Outpatient Clinic, […]

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Neuroendocrine, Autonomic, and Metabolic Responses to an Orexin Antagonist,  Suvorexant, in Psychiatric Patients with Insomnia

Neuroendocrine, Autonomic, and Metabolic Responses to an Orexin Antagonist, Suvorexant, in Psychiatric Patients with Insomnia

| April 1, 2017 | 0 Comments

by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine, Kosekai-Kusatsu Hospital, in Hiroshima, Japan, and Dr. Nagamine is with the Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, in Yamaguchi, Japan. Innov Clin Neurosci. 2017;14(3–4):30–37 Funding: No funding was received for the preparation […]

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Redefining Acute Relapses in Multiple Sclerosis: Implications for Phase 3 Clinical Trials and Treatment Algorithms

Redefining Acute Relapses in Multiple Sclerosis: Implications for Phase 3 Clinical Trials and Treatment Algorithms

| April 1, 2017 | 0 Comments

by Jagannadha Avasarala, MD, PhD Dr. Avasarala is with the Department of Internal Medicine, Division of Neurology, Greenville Health System, Neuroscience Associates, in Greenville, South Carolina. Innov Clin Neurosci. 2017;14(3–4):38–40 Funding: No funding was received for the preparation of this article. Financial disclosures: The author has no conflicts of interest relevant to the content of […]

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Managing Your Aging  Patient Population

Managing Your Aging Patient Population

| April 1, 2017 | 0 Comments

by Ann L. McNary, JD Ms. McNary is Senior Risk Manager at PRMS, Inc. in Arlington, Virginia. Innov Clin Neurosci. 2017;14(3–4)41–44 This ongoing column is dedicated to providing information to our readers on managing legal risks associated with medical practice. We invite questions from our readers. The answers are provided by PRMS, Inc. (www.prms.com), a […]

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Letter to the editor: Modafinil Augmentation Therapy in Patient with Traumatic Brain Injury

Letter to the editor: Modafinil Augmentation Therapy in Patient with Traumatic Brain Injury

| April 1, 2017 | 0 Comments

Innov Clin Neurosci. 2017;14(3–4):11 Dear Editor: Traumatic brain injury (TBI) is a significant cause of morbidity and mortality. Annually, more than two million people in the United States will sustain a TBI, and approximately one quarter of those will require hospitalization. Of those who survive TBI, many continue to suffer from a variety of symptoms, […]

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CNS Summit 2016 Abstracts of Poster Presentations

CNS Summit 2016 Abstracts of Poster Presentations

| February 1, 2017 | 0 Comments

Innov Clin Neurosci. 2017;14(1–2)3–23 A MESSAGE FROM THE EDITOR Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that was presented during CNS Summit 2016, which was held October 27 […]

Continue Reading