Innovations in Clinical Neuroscience

Click here to submit a manuscript.

Click here to submit a manuscript.

 

Providing evidence-based information in a practical, easy-to-read format for practicing clinicians, investigators, industry scientists, and other entities involved in the field of neuroscience

VOLUME 13, ISSUE 9–10, SEPTEMBER–OCTOBER 2016

Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

Editor’s Message: September–October 2016 Issue Highlights

Editor’s Message: September–October 2016 Issue Highlights

Dear Colleagues: Welcome to the September-October 2016 issue of Innovations in Clinical Neuroscience (ICNS). As the official journal of the CNS Summit, the International Society for CNS Drug Development (ISCDD), and the International Society for CNS Clinical Trials and Methodology (ISCTM), an important part of our editorial mission is to accelerate and enhance the development […]

Continue Reading

Performance, Reliability, Usability, and Safety of the ID-Cap System for Ingestion Event Monitoring in Healthy Volunteers:  A Pilot Study

Performance, Reliability, Usability, and Safety of the ID-Cap System for Ingestion Event Monitoring in Healthy Volunteers: A Pilot Study

by Glen P. Flores, PhD; Brian Peace, BS; Tony C. Carnes, PhD; Susan L. Baumgartner, PharmD, MBA; D. Eric Buffkin, Jr., MBA; Neil R. Euliano, PhD; and Larry N. Smith, MD, FACS Drs. Flores, Carnes, Euliano, Mr. Peace, and Mr. Buffkin are with etectRx, Inc. in Newberry, Florida; and Drs. Baumgartner and Smith are from […]

Continue Reading

The Depression Inventory Development Workgroup: A Collaborative, Empirically Driven Initiative to Develop a New Assessment Tool for Major Depressive Disorder

The Depression Inventory Development Workgroup: A Collaborative, Empirically Driven Initiative to Develop a New Assessment Tool for Major Depressive Disorder

by Anthony L. Vaccarino, PhD; Kenneth R. Evans, PhD; Amir H. Kalali, MD; Sidney H. Kennedy, MD, FRCPC; Nina Engelhardt, PhD; Benico N. Frey, MD, MSc, PhD; John H. Greist, MD; Kenneth A. Kobak, PhD; Raymond W. Lam, MD, FRCPC; Glenda MacQueen, MD, PhD, FRCPC; Roumen Milev, MD, PhD, FRCPC, FRCPsych; Franca M. Placenza, PhD; Arun […]

Continue Reading

Assessment of Cognitive and Neurologic Recovery in Ischemic Stroke Drug Trials: Results from a Randomized, Double-blind, Placebo-controlled Study

Assessment of Cognitive and Neurologic Recovery in Ischemic Stroke Drug Trials: Results from a Randomized, Double-blind, Placebo-controlled Study

by Franco Di Cesare, MD; Jessica Mancuso, PhD; Brian Silver, MD; and Peter T. Loudon, PhD Dr. Di Cesare is with Leoben Research Limited in Glasgow, UK; Dr. Mancuso is with Research Statistics at Pfizer in Groton, Connecticut, USA; Dr. Silver is with Rhode Island Hospital and Alpert Medical School of Brown University in Providence, Rhode […]

Continue Reading

Eszopiclone-induced Parasomnia with Suicide Attempt: A Case Report

Eszopiclone-induced Parasomnia with Suicide Attempt: A Case Report

by J. Gibson Pennington, MD, and Jeffrey Guina, MD From Wright-Patterson Air Force Base and Wright State University Boonshoft School of Medicine Department of Psychiatry, Dayton, Ohio Innov Clin Neurosci. 2016;13(9–10):44–48 Funding: No funding was provided for the preparation of this article. Financial Disclosures: The authors have no financial dislosures relevant to the content of […]

Continue Reading

PAST ARTICLES (user login required)

Editor’s Message—Issue Highlights, July–August 2016

Editor’s Message—Issue Highlights, July–August 2016

Dear Colleagues: Welcome to the July–August 2016 issue of Innovations in Clinical Neuroscience. We start this issue with an interesting study by MacEwan et al titled, “Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases.” Here, the authors assessed the level of private and public investment in research and development […]

Continue Reading

Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases

Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases

by Joanna P. MacEwan, PhD; Seth Seabury, PhD; Myrlene Sanon Aigbogun, MPH; Siddhesh Kamat, MS, MBA; Emma van Eijndhoven, MS, MA; Clement Francois, PhD; Crystal Henderson, PharmD, BCPP; and Leslie Citrome, MD, MPH Dr. MacEwan and Ms. van Eijndhoven are with Precision Health Economics in Los Angeles, California, USA; Dr. Seabury is with the University […]

Continue Reading

Brexpiprazole: A New Treatment Option for Schizophrenia

Brexpiprazole: A New Treatment Option for Schizophrenia

by Jonathan R. Scarff, MD Dr. Scarff is with Veterans Affairs Outpatient Clinic, Spartanburg, South Carolina. Innov Clin Neurosci. 2016;13(7–8):26–29

Continue Reading

The Potential Role  of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis

The Potential Role of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis

by Nazanin Arjomand Fard, MSci; Gholamreza Azizi, PhD; and Abbas Mirshafiey, PhD Dr. Fard is with Kish International Campus, University of Tehran, Tehran, Iran; Dr. Azizi is with Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran and Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran; and […]

Continue Reading

A Case of Treatment-resistant Depression and Body Dysmorphic Disorder: The Role of Electroconvulsive Therapy Revisited

A Case of Treatment-resistant Depression and Body Dysmorphic Disorder: The Role of Electroconvulsive Therapy Revisited

by Ram S. Mahato, MD; Maria Chona P. San Gabriel, MD; Carrol T. Longshore, MD; and David B. Schnur, MD The authors are with the Department of Psychiatry at Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, New York. Innov Clin Neurosci. 2016;13(7–8):37–40

Continue Reading

Professional Liability for Forensic Activities:  Liability Without a Treatment Relationship

Professional Liability for Forensic Activities: Liability Without a Treatment Relationship

by Donna Vanderpool, MBA, JD Ms. Vanderpool is Vice President of Risk Management at PRMS, Inc., Arlington, Virginia. Innov Clin Neurosci. 2016;13(7–8):41–44

Continue Reading

THE NEUROSCIENCE REPORT

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

Continue Reading

The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information.   This […]

Continue Reading

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

Continue Reading

The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

Continue Reading

The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

Continue Reading

The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

Continue Reading

SPECIAL ISSUES AND SUPPLEMENTS

Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

Hot Topics in Pain Management

Hot Topics in Pain Management

CLICK HERE TO ACCESS E-EDITION Past Issues                   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at […]

Continue Reading

Hot Topics in Drug Development

Hot Topics in Drug Development

Hot Topics in Drug Development PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

Current Trends in Epilepsy Management

Current Trends in Epilepsy Management

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

Supplement to Nov-Dec 2015 Issue: Abstracts of  Poster Presentations: CNS Summit 2015

Supplement to Nov-Dec 2015 Issue: Abstracts of Poster Presentations: CNS Summit 2015

October 7–11, 2015 Boca Raton, Florida Innov Clin Neurosci. 2015;12(11–12 Suppl C):3–17 CNS Drug Compounds Synthesis of carnitine analogues for inhibition of carnitine palmitoyltransferase Presenters: Bornstein J, Garneau-Tsodikova S Affiliations: University of Michigan Life Sciences Institute Background: Type 2 diabetes (T2DM) carries a markedly elevated risk of cerebrovascular disease. Carnitine plays a key role transporting […]

Continue Reading

Supplement to May–June 2015 Issue: CNS Summit 2014 Abstracts of  Poster Presentations

Supplement to May–June 2015 Issue: CNS Summit 2014 Abstracts of Poster Presentations

Innov Clin Neurosci. 2015;12(5–6 Suppl B):3–19 Click here to access the e-Edition, a digital replica of the printed version. CNS Drug Compounds/Therapies/Devices Long-acting injectable antipsychotics (LAIs) in outpatient treatment of DMS-IV-R schizophrenia Presenters: Bellnier T, Patil K, Ortega T, Seeger G Affiliations: SUNY University at Buffalo, GPI Clinical Research Background: The treatment of schizophrenia with […]

Continue Reading

Other Recent Posts

Current e-Edition

Current e-Edition

| October 9, 2016 | 0 Comments

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

| December 6, 2016 | 0 Comments

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

Continue Reading

The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

| November 11, 2016 | 1 Comment

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information.   This […]

Continue Reading

Editor’s Message: September–October 2016 Issue Highlights

Editor’s Message: September–October 2016 Issue Highlights

| October 9, 2016 | 0 Comments

Dear Colleagues: Welcome to the September-October 2016 issue of Innovations in Clinical Neuroscience (ICNS). As the official journal of the CNS Summit, the International Society for CNS Drug Development (ISCDD), and the International Society for CNS Clinical Trials and Methodology (ISCTM), an important part of our editorial mission is to accelerate and enhance the development […]

Continue Reading

Performance, Reliability, Usability, and Safety of the ID-Cap System for Ingestion Event Monitoring in Healthy Volunteers:  A Pilot Study

Performance, Reliability, Usability, and Safety of the ID-Cap System for Ingestion Event Monitoring in Healthy Volunteers: A Pilot Study

| October 9, 2016 | 0 Comments

by Glen P. Flores, PhD; Brian Peace, BS; Tony C. Carnes, PhD; Susan L. Baumgartner, PharmD, MBA; D. Eric Buffkin, Jr., MBA; Neil R. Euliano, PhD; and Larry N. Smith, MD, FACS Drs. Flores, Carnes, Euliano, Mr. Peace, and Mr. Buffkin are with etectRx, Inc. in Newberry, Florida; and Drs. Baumgartner and Smith are from […]

Continue Reading

The Depression Inventory Development Workgroup: A Collaborative, Empirically Driven Initiative to Develop a New Assessment Tool for Major Depressive Disorder

The Depression Inventory Development Workgroup: A Collaborative, Empirically Driven Initiative to Develop a New Assessment Tool for Major Depressive Disorder

| October 9, 2016 | 0 Comments

by Anthony L. Vaccarino, PhD; Kenneth R. Evans, PhD; Amir H. Kalali, MD; Sidney H. Kennedy, MD, FRCPC; Nina Engelhardt, PhD; Benico N. Frey, MD, MSc, PhD; John H. Greist, MD; Kenneth A. Kobak, PhD; Raymond W. Lam, MD, FRCPC; Glenda MacQueen, MD, PhD, FRCPC; Roumen Milev, MD, PhD, FRCPC, FRCPsych; Franca M. Placenza, PhD; Arun […]

Continue Reading

Assessment of Cognitive and Neurologic Recovery in Ischemic Stroke Drug Trials: Results from a Randomized, Double-blind, Placebo-controlled Study

Assessment of Cognitive and Neurologic Recovery in Ischemic Stroke Drug Trials: Results from a Randomized, Double-blind, Placebo-controlled Study

| October 9, 2016 | 0 Comments

by Franco Di Cesare, MD; Jessica Mancuso, PhD; Brian Silver, MD; and Peter T. Loudon, PhD Dr. Di Cesare is with Leoben Research Limited in Glasgow, UK; Dr. Mancuso is with Research Statistics at Pfizer in Groton, Connecticut, USA; Dr. Silver is with Rhode Island Hospital and Alpert Medical School of Brown University in Providence, Rhode […]

Continue Reading

Eszopiclone-induced Parasomnia with Suicide Attempt: A Case Report

Eszopiclone-induced Parasomnia with Suicide Attempt: A Case Report

| October 9, 2016 | 0 Comments

by J. Gibson Pennington, MD, and Jeffrey Guina, MD From Wright-Patterson Air Force Base and Wright State University Boonshoft School of Medicine Department of Psychiatry, Dayton, Ohio Innov Clin Neurosci. 2016;13(9–10):44–48 Funding: No funding was provided for the preparation of this article. Financial Disclosures: The authors have no financial dislosures relevant to the content of […]

Continue Reading

Cariprazine for Schizophrenia and Bipolar Disorder

Cariprazine for Schizophrenia and Bipolar Disorder

| October 8, 2016 | 0 Comments

by Jonathan R. Scarff, MD Dr. Scarff is a staff psychiatrist at the Veterans Affairs Outpatient Clinic in Spartanburg, South Carolina, USA Innov Clin Neurosci. 2016;13(9–10):49–52 Funding: The author has received no financial support for the writing of this manuscript. Financial Disclosures: The authors has no financial dislosures relevant to the content of this article. […]

Continue Reading

Consent to Treatment of Minors, Revisited

Consent to Treatment of Minors, Revisited

| October 8, 2016 | 0 Comments

by Ann McNary, JD Ms. McNary is Senior Risk Manager at PRMS, Inc. in Arlington, Virginia. Innov Clin Neurosci. 2016;13(9–10)53–55 This ongoing column is dedicated to providing information to our readers on managing legal risks associated with medical practice. We invite questions from our readers. The answers are provided by PRMS, Inc. (www.prms.com), a manager […]

Continue Reading