Innovations in Clinical Neuroscience

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VOLUME 14, ISSUE 1–2, JANUARY-FEBRUARY 2017

Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Editor’s Message: Issue Highlights, January–February 2017

Editor’s Message: Issue Highlights, January–February 2017

Dear Colleagues: Welcome to the January–February 2017 issue of Innovations in Clinical Neuroscience. We start our 14th year of publication strong with an interesting and diverse issue we hope you enjoy as much as we did putting it together. In the review article by Dascal et al, “Virtual Reality and Medical Inpatients: A Systematic Review […]

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Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials

Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials

by Julieta Dascal, BA; Mark Reid, PhD; Waguih William Ishak, MD, FAPA; Brennan Spiegel, MD, FACG; Jennifer Recacho, MA; Bradley Rosen, MD; and Itai Danovitch, MD, MBA All authors are from Cedars-Sinai Medical Center, Department of Psychiatry and Behavioral Neurosciences in Los Angeles, California. Innov Clin Neurosci. 2017;14(1–2):14–21 Funding: No funding was received for the […]

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Outcomes Assessment in Clinical Trials of Alzheimer’s Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs

Outcomes Assessment in Clinical Trials of Alzheimer’s Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs

by Holly Posner, MD, MS; Rosie Curiel, PsyD; Chris Edgar, PhD; Suzanne Hendrix, PhD; Enchi Liu, PhD; David A. Loewenstein, PhD; Glenn Morrison, MSc, PhD; Leslie Shinobu, PhD; Keith Wesnes, BSc, PhD, FSS, CPsychol, FBPsS; and Philip D. Harvey, PhD Dr. Posner is with Pfizer Inc., New York, New York; Drs. Curiel, Loewenstein, and Harvey […]

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Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer’s Disease Spectrum

Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer’s Disease Spectrum

by Philip D. Harvey, PhD; Stephanie Cosentino, PhD; Rosie Curiel, PhD; Terry E. Goldberg, PhD; Jeffrey Kaye, MD; David Loewenstein, PhD; Daniel Marson, PhD, JD; David Salmon, PhD; Keith Wesnes, PhD; and Holly Posner, MD Drs. Harvey, Curiel, and Loewenstein are with the University of Miami Leonard Miller School of Medicine, Department of Psychiatry and Behavioral Sciences, Miami, Florida; […]

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Behavioral and Stereological Analysis of the Effects of Intermittent Feeding Diet on the Orally Administrated MDMA (“ecstasy”) in Mice

Behavioral and Stereological Analysis of the Effects of Intermittent Feeding Diet on the Orally Administrated MDMA (“ecstasy”) in Mice

by Zeinab Ebrahimian, MSc; Zeinab Karimi, MSc; Mohammad Javad Khoshnoud, Pharm D, PhD; Mohammad Reza Namavar, PhD; Bahram Daraei, PharmD, PhD; and Moshen Raza Haidari, MD, PhD Drs. Ebrahimian and Khoshnoud are with the Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shiraz University of Medical Sciences in Shiraz, IR Iran; Drs. Karimi and Daraei […]

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PAST ARTICLES (user login required)

Editors Message and Issue Highlights: November–December 2016

Editors Message and Issue Highlights: November–December 2016

Dear Colleagues: Welcome to the November–December 2016 issue of Innovations in Clinical Neuroscience. We begin this issue with a thoughtful review and commentary by Calabró et al titled, “The Right to Die in Chronic Disorders of Consciousness: Can We Avoid the Slippery Slope Argument?” Here the authors review current opinions and ethical issues concerning end-of-life […]

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The Right to Die in Chronic Disorders of Consciousness: Can We Avoid the Slippery Slope Argument?

The Right to Die in Chronic Disorders of Consciousness: Can We Avoid the Slippery Slope Argument?

by Rocco Salvatore Calabrò, MD, PhD; Antonino Naro, MD, PhD; Rosaria De Luca, MS, PhD; Margherita Russo, MD, PhD; Lory Caccamo, PhD; Alfredo Manuli, MS; Alessia Bramanti; and Placido Bramanti, MD Drs. Calabró, Naro, de Luca, Russo, Manuli, A. Bramanti, and P. Bramanti are from the IRCCS Centro Neurolesi “Bonino-Pulejo” in Messina, Italy; and Dr. […]

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Acute Hyperglycemia Associated with Psychotic Symptoms in a Patient with Type 1 Diabetes Mellitus: A Case Report

Acute Hyperglycemia Associated with Psychotic Symptoms in a Patient with Type 1 Diabetes Mellitus: A Case Report

by Swapnajeet Sahoo, MD; Aseem Mehra, MD; and Sandeep Grover, MD All from the Department of Psychiatry at the Postgraduate Institute of Medical Education and Research in Chandigarh, India Innov Clin Neurosci. 2016;13(11–12):25–27

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Complete Recovery from Cardiac Arrest Caused by Risperidone-induced Hypothermia

Complete Recovery from Cardiac Arrest Caused by Risperidone-induced Hypothermia

by Takahiko Nagamine, MD, PhD Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Yamaguchi, Japan. Innov Clin Neurosci. 2016;13(11–12):28–31

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Sympathetic Nerve Entrapment Point Injection as an Antireflux Procedure for Refractory Laryngopharyngeal Reflux: A First Case Report of Innovative Autonomic Regulation

Sympathetic Nerve Entrapment Point Injection as an Antireflux Procedure for Refractory Laryngopharyngeal Reflux: A First Case Report of Innovative Autonomic Regulation

by Sangsoo Lee, MD, MSc; Chang Jin Oh, MD; and Jeong Won Seong, MD Dr. Lee is with the Department of Psychiatry at Ahav Hospital, South Korea; Dr. Oh is with the Department of Pain Medicine and Anesthesiology at the Seoul Samsung Union Clinic in South Korea; and Dr. Seong is with the Department of […]

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Ransomware: Minimizing the Risks

Ransomware: Minimizing the Risks

by Justin Pope, JD Mr. Pope is Associate Risk Manager at PRMS, Inc. in Arlington, Virginia. Innov Clin Neurosci. 2016;13(11–12)37–40

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THE NEUROSCIENCE REPORT

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

The Neuroscience Report—Volume 47 (December 6, 2016): Psychology of Technology in Society

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

The Neuroscience Report—Volume 46 (November 11, 2016): Accessibility of Mental Healthcare

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information.   This […]

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The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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SPECIAL ISSUES AND SUPPLEMENTS

Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Hot Topics in Pain Management

Hot Topics in Pain Management

CLICK HERE TO ACCESS E-EDITION Past Issues                   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at […]

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Hot Topics in Drug Development

Hot Topics in Drug Development

Hot Topics in Drug Development PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Current Trends in Epilepsy Management

Current Trends in Epilepsy Management

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Supplement to Nov-Dec 2015 Issue: Abstracts of  Poster Presentations: CNS Summit 2015

Supplement to Nov-Dec 2015 Issue: Abstracts of Poster Presentations: CNS Summit 2015

October 7–11, 2015 Boca Raton, Florida Innov Clin Neurosci. 2015;12(11–12 Suppl C):3–17 CNS Drug Compounds Synthesis of carnitine analogues for inhibition of carnitine palmitoyltransferase Presenters: Bornstein J, Garneau-Tsodikova S Affiliations: University of Michigan Life Sciences Institute Background: Type 2 diabetes (T2DM) carries a markedly elevated risk of cerebrovascular disease. Carnitine plays a key role transporting […]

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Supplement to May–June 2015 Issue: CNS Summit 2014 Abstracts of  Poster Presentations

Supplement to May–June 2015 Issue: CNS Summit 2014 Abstracts of Poster Presentations

Innov Clin Neurosci. 2015;12(5–6 Suppl B):3–19 Click here to access the e-Edition, a digital replica of the printed version. CNS Drug Compounds/Therapies/Devices Long-acting injectable antipsychotics (LAIs) in outpatient treatment of DMS-IV-R schizophrenia Presenters: Bellnier T, Patil K, Ortega T, Seeger G Affiliations: SUNY University at Buffalo, GPI Clinical Research Background: The treatment of schizophrenia with […]

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Other Recent Posts

Current e-Edition

Current e-Edition

| February 1, 2017 | 0 Comments

CLICK HERE TO ACCESS E-EDITION   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

Editor’s Message: Issue Highlights, January–February 2017

Editor’s Message: Issue Highlights, January–February 2017

| February 1, 2017 | 0 Comments

Dear Colleagues: Welcome to the January–February 2017 issue of Innovations in Clinical Neuroscience. We start our 14th year of publication strong with an interesting and diverse issue we hope you enjoy as much as we did putting it together. In the review article by Dascal et al, “Virtual Reality and Medical Inpatients: A Systematic Review […]

Continue Reading

Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials

Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials

| February 1, 2017 | 0 Comments

by Julieta Dascal, BA; Mark Reid, PhD; Waguih William Ishak, MD, FAPA; Brennan Spiegel, MD, FACG; Jennifer Recacho, MA; Bradley Rosen, MD; and Itai Danovitch, MD, MBA All authors are from Cedars-Sinai Medical Center, Department of Psychiatry and Behavioral Neurosciences in Los Angeles, California. Innov Clin Neurosci. 2017;14(1–2):14–21 Funding: No funding was received for the […]

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Outcomes Assessment in Clinical Trials of Alzheimer’s Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs

Outcomes Assessment in Clinical Trials of Alzheimer’s Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs

| February 1, 2017 | 0 Comments

by Holly Posner, MD, MS; Rosie Curiel, PsyD; Chris Edgar, PhD; Suzanne Hendrix, PhD; Enchi Liu, PhD; David A. Loewenstein, PhD; Glenn Morrison, MSc, PhD; Leslie Shinobu, PhD; Keith Wesnes, BSc, PhD, FSS, CPsychol, FBPsS; and Philip D. Harvey, PhD Dr. Posner is with Pfizer Inc., New York, New York; Drs. Curiel, Loewenstein, and Harvey […]

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Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer’s Disease Spectrum

Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer’s Disease Spectrum

| February 1, 2017 | 0 Comments

by Philip D. Harvey, PhD; Stephanie Cosentino, PhD; Rosie Curiel, PhD; Terry E. Goldberg, PhD; Jeffrey Kaye, MD; David Loewenstein, PhD; Daniel Marson, PhD, JD; David Salmon, PhD; Keith Wesnes, PhD; and Holly Posner, MD Drs. Harvey, Curiel, and Loewenstein are with the University of Miami Leonard Miller School of Medicine, Department of Psychiatry and Behavioral Sciences, Miami, Florida; […]

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Behavioral and Stereological Analysis of the Effects of Intermittent Feeding Diet on the Orally Administrated MDMA (“ecstasy”) in Mice

Behavioral and Stereological Analysis of the Effects of Intermittent Feeding Diet on the Orally Administrated MDMA (“ecstasy”) in Mice

| February 1, 2017 | 0 Comments

by Zeinab Ebrahimian, MSc; Zeinab Karimi, MSc; Mohammad Javad Khoshnoud, Pharm D, PhD; Mohammad Reza Namavar, PhD; Bahram Daraei, PharmD, PhD; and Moshen Raza Haidari, MD, PhD Drs. Ebrahimian and Khoshnoud are with the Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shiraz University of Medical Sciences in Shiraz, IR Iran; Drs. Karimi and Daraei […]

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MicroRNAs as Biomarkers for Psychiatric Conditions:  A Review of Current Research

MicroRNAs as Biomarkers for Psychiatric Conditions: A Review of Current Research

| February 1, 2017 | 0 Comments

by Anoop Narahari, MD; Mariyah Hussain, MD; and Venkatesh Sreeram, MD Drs. Narahari, Hussain, and Sreeram are from the University of Alabama, Department of Psychiatry and Behavioral sciences, Birmingham, Alabama. Innov Clin Neurosci. 2017;14(1–2):53–55 Funding: No funding was received for the preparation of this article. Financial disclosures: The authors have no conflicts of interest relevant to […]

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Ketamine Therapy for Treatment-resistant Depression in a Patient with Multiple Sclerosis: A Case Report

Ketamine Therapy for Treatment-resistant Depression in a Patient with Multiple Sclerosis: A Case Report

| February 1, 2017 | 0 Comments

by Michael M. Messer, MD, and Irina V. Haller, PhD, MS Dr. Messer is with Behavioral Health Department, Essentia Health, Duluth, MN, and Dr. Haller is with Essentia Institute of Rural Health, Essentia Health, Duluth, MN, USA. Innov Clin Neurosci. 2017;14(1–2):56–59 Funding: This research had no grant funding from any funding agency in the public, […]

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Risk Management Issues When Taking Locum Tenens Assignments

Risk Management Issues When Taking Locum Tenens Assignments

| February 1, 2017 | 0 Comments

by Charles D. Cash, JD, LLM Mr. Cash is Assistant Vice President of Risk Management at PRMS, Inc., Arlington, Virginia. Innov Clin Neurosci. 2017;14(1–2)60–62 This ongoing column is dedicated to providing information to our readers on managing legal risks associated with medical practice. We invite questions from our readers. The answers are provided by PRMS, […]

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Letters to the Editor: Discussing sexual health after traumatic brain injury: an unmet need!

Letters to the Editor: Discussing sexual health after traumatic brain injury: an unmet need!

| February 1, 2017 | 0 Comments

Innov Clin Neurosci. 2017;14(1–2):11–12 Dear Editor: Sexual dysfunction (SD) after traumatic brain injury (TBI) is an often neglected and underreported issue within the medical field.[1,2] A recent interesting work by Bivona et al[1] found that TBI survivors and their partners showed a decrease in sexual desire and frequency of sexual intercourse, particularly those who suffered […]

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