Innovations in Clinical Neuroscience

Providing evidence-based information in a practical, easy-to-read format for practicing clinicians, investigators, industry scientists, and other entities involved in the field of neuroscience

VOLUME 13, ISSUE 7–8, JULY–AUGUST 2016

Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Editor’s Message—Issue Highlights, July–August 2016

Editor’s Message—Issue Highlights, July–August 2016

Dear Colleagues: Welcome to the July–August 2016 issue of Innovations in Clinical Neuroscience. We start this issue with an interesting study by MacEwan et al titled, “Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases.” Here, the authors assessed the level of private and public investment in research and development […]

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Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases

Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases

by Joanna P. MacEwan, PhD; Seth Seabury, PhD; Myrlene Sanon Aigbogun, MPH; Siddhesh Kamat, MS, MBA; Emma van Eijndhoven, MS, MA; Clement Francois, PhD; Crystal Henderson, PharmD, BCPP; and Leslie Citrome, MD, MPH Dr. MacEwan and Ms. van Eijndhoven are with Precision Health Economics in Los Angeles, California, USA; Dr. Seabury is with the University […]

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Brexpiprazole: A New Treatment Option for Schizophrenia

Brexpiprazole: A New Treatment Option for Schizophrenia

by Jonathan R. Scarff, MD Dr. Scarff is with Veterans Affairs Outpatient Clinic, Spartanburg, South Carolina. Innov Clin Neurosci. 2016;13(7–8):26–29 Funding: No funding was received for the preparation of this manuscript. Financial disclosures: The author has no financial disclosures relevant to the content of this article. Key words: Schizophrenia, brexpiprazole, antipsychotic Abstract: Schizophrenia occurs in […]

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The Potential Role  of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis

The Potential Role of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis

by Nazanin Arjomand Fard, MSci; Gholamreza Azizi, PhD; and Abbas Mirshafiey, PhD Dr. Fard is with Kish International Campus, University of Tehran, Tehran, Iran; Dr. Azizi is with Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran and Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran; and […]

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A Case of Treatment-resistant Depression and Body Dysmorphic Disorder: The Role of Electroconvulsive Therapy Revisited

A Case of Treatment-resistant Depression and Body Dysmorphic Disorder: The Role of Electroconvulsive Therapy Revisited

by Ram S. Mahato, MD; Maria Chona P. San Gabriel, MD; Carrol T. Longshore, MD; and David B. Schnur, MD The authors are with the Department of Psychiatry at Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, New York. Innov Clin Neurosci. 2016;13(7–8):37–40 Funding: No funding was received for the preparation of […]

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PAST ARTICLES (user login required)

Editor’s Message and May–June 2016 Issue Highlights

Editor’s Message and May–June 2016 Issue Highlights

Dear Colleagues: Welcome to the May–June 2016 issue of Innovations in Clinical Neuroscience. I am pleased to start the issue with the first of a series of articles we’ll be publishing that will explore the emerging field of digital medicine and how innovative technology can improve patient outcomes in the field of neuroscience. I am […]

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Digital Suicide Prevention: Can Technology Become a Game-changer?

Digital Suicide Prevention: Can Technology Become a Game-changer?

by Arshya Vahabzadeh, MD; Ned Sahin, PhD; and Amir Kalali, MD Dr. Vahabzadeh is Director of Digital Health, Brain Power, in Cambridge, Massachusetts; Instructor in Psychiatry, Harvard Medical School in Cambridge, Massachusetts; and Innovation Officer at Massachusetts General Hospital Psychiatry Academy in Boston, Massachusetts. Dr. Sahin is Chief Science Officer at Brain Power and Associate […]

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Editor’s Message and Issue Highlights

Editor’s Message and Issue Highlights

Dear Colleagues: Welcome to the March–April 2016 issue of Innovations in Clinical Neuroscience (ICNS). Attitudes regarding marijuana use have changed dramatically over the past 50-plus years in the United States. According to data from the Pew Research Center, support for the legalization of marijuana has gone from 12 percent of the American population in favor […]

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Why Not Pot? A Review of the Brain-based Risks of Cannabis

Why Not Pot? A Review of the Brain-based Risks of Cannabis

by Kai MacDonald, MD, and Katherine Pappas, BA Dr. MacDonald and Ms. Pappas are with UC San Diego Psychiatry, San Diego, CA, USA Innov Clin Neurosci. 2016;13(3–4):13–22 Funding: Dr. MacDonald’s work is sponsored in part by the Goodenough Neuroscience Research Fund. Financial disclosures: The authors have no conflicts of interest relevant to the content of […]

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Medical Marijuana for Epilepsy?

Medical Marijuana for Epilepsy?

by Murali K. Kolikonda, MD; Kavitha Srinivasan, MD; Manasa Enja, MD; Vishwanath Sagi, MD; and Steven Lippmann, MD Drs. Kolikonda and Sagi are from the Department of Neurology, Dr. Srinivasan is from the Clinical Translational Research Support Unit, and Drs. Enja and Lippmann are from the Department of Psychiatry, University of Louisville School of Medicine, […]

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Editor’s Message and Issue Highlights, January–February 2016

Editor’s Message and Issue Highlights, January–February 2016

Dear Colleagues: Welcome to the January–February 2016 issue of Innovations in Clinical Neuroscience. We start this issue with the article “Erectile Dysfunction in Individuals with Neurologic Disability: A Hospital-based Cross-sectional Study,” by Calabró et al. Here, the investigators evaluated the prevalence and causes of erectile dysfunction in a group of hospital inpatients suffering from neurologic […]

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THE NEUROSCIENCE REPORT

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The Neuroscience Report—Volume 43 (June 25, 2016): Medical Marijuana in Neuroscience

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The Neuroscience Report—Volume 42 (June 13, 2016): Neuroethics

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 41 (May 20, 2016): Human Brain vs. Artificial Intelligence

The Neuroscience Report—Volume 41 (May 20, 2016): Human Brain vs. Artificial Intelligence

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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The Neuroscience Report—Volume 40 (May 6, 2016): Anti-addiction Medications

The Neuroscience Report—Volume 40 (May 6, 2016): Anti-addiction Medications

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

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SPECIAL ISSUES AND SUPPLEMENTS

Hot Topics in Pain Management

Hot Topics in Pain Management

CLICK HERE TO ACCESS E-EDITION Past Issues                   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at […]

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Current e-Edition

Current e-Edition

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Hot Topics in Drug Development

Hot Topics in Drug Development

Hot Topics in Drug Development PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Current Trends in Epilepsy Management

Current Trends in Epilepsy Management

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

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Supplement to Nov-Dec 2015 Issue: Abstracts of  Poster Presentations: CNS Summit 2015

Supplement to Nov-Dec 2015 Issue: Abstracts of Poster Presentations: CNS Summit 2015

October 7–11, 2015 Boca Raton, Florida Innov Clin Neurosci. 2015;12(11–12 Suppl C):3–17 CNS Drug Compounds Synthesis of carnitine analogues for inhibition of carnitine palmitoyltransferase Presenters: Bornstein J, Garneau-Tsodikova S Affiliations: University of Michigan Life Sciences Institute Background: Type 2 diabetes (T2DM) carries a markedly elevated risk of cerebrovascular disease. Carnitine plays a key role transporting […]

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Supplement to May–June 2015 Issue: CNS Summit 2014 Abstracts of  Poster Presentations

Supplement to May–June 2015 Issue: CNS Summit 2014 Abstracts of Poster Presentations

Innov Clin Neurosci. 2015;12(5–6 Suppl B):3–19 Click here to access the e-Edition, a digital replica of the printed version. CNS Drug Compounds/Therapies/Devices Long-acting injectable antipsychotics (LAIs) in outpatient treatment of DMS-IV-R schizophrenia Presenters: Bellnier T, Patil K, Ortega T, Seeger G Affiliations: SUNY University at Buffalo, GPI Clinical Research Background: The treatment of schizophrenia with […]

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Other Recent Posts

Current e-Edition

Current e-Edition

| August 1, 2016 | 0 Comments

CLICK HERE TO ACCESS E-EDITION PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at the top of the window.

Continue Reading

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

The Neuroscience Report—Volume 45 (September 15, 2016): Schizophrenia

| September 15, 2016 | 0 Comments

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s […]

Continue Reading

Hot Topics in Pain Management

Hot Topics in Pain Management

| August 28, 2016 | 0 Comments

CLICK HERE TO ACCESS E-EDITION Past Issues                   PDFs can be downloaded and printed from the e-Editions. Click on the above issue issue, find the article, then click on the print command. For archived e-editions, click on the image above, then click on the folder icon at […]

Continue Reading

Editor’s Message—Issue Highlights, July–August 2016

Editor’s Message—Issue Highlights, July–August 2016

| August 1, 2016 | 0 Comments

Dear Colleagues: Welcome to the July–August 2016 issue of Innovations in Clinical Neuroscience. We start this issue with an interesting study by MacEwan et al titled, “Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases.” Here, the authors assessed the level of private and public investment in research and development […]

Continue Reading

Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases

Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases

| August 1, 2016 | 0 Comments

by Joanna P. MacEwan, PhD; Seth Seabury, PhD; Myrlene Sanon Aigbogun, MPH; Siddhesh Kamat, MS, MBA; Emma van Eijndhoven, MS, MA; Clement Francois, PhD; Crystal Henderson, PharmD, BCPP; and Leslie Citrome, MD, MPH Dr. MacEwan and Ms. van Eijndhoven are with Precision Health Economics in Los Angeles, California, USA; Dr. Seabury is with the University […]

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Brexpiprazole: A New Treatment Option for Schizophrenia

Brexpiprazole: A New Treatment Option for Schizophrenia

| August 1, 2016 | 0 Comments

by Jonathan R. Scarff, MD Dr. Scarff is with Veterans Affairs Outpatient Clinic, Spartanburg, South Carolina. Innov Clin Neurosci. 2016;13(7–8):26–29 Funding: No funding was received for the preparation of this manuscript. Financial disclosures: The author has no financial disclosures relevant to the content of this article. Key words: Schizophrenia, brexpiprazole, antipsychotic Abstract: Schizophrenia occurs in […]

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The Potential Role  of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis

The Potential Role of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis

| August 1, 2016 | 0 Comments

by Nazanin Arjomand Fard, MSci; Gholamreza Azizi, PhD; and Abbas Mirshafiey, PhD Dr. Fard is with Kish International Campus, University of Tehran, Tehran, Iran; Dr. Azizi is with Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran and Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran; and […]

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A Case of Treatment-resistant Depression and Body Dysmorphic Disorder: The Role of Electroconvulsive Therapy Revisited

A Case of Treatment-resistant Depression and Body Dysmorphic Disorder: The Role of Electroconvulsive Therapy Revisited

| August 1, 2016 | 0 Comments

by Ram S. Mahato, MD; Maria Chona P. San Gabriel, MD; Carrol T. Longshore, MD; and David B. Schnur, MD The authors are with the Department of Psychiatry at Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, New York. Innov Clin Neurosci. 2016;13(7–8):37–40 Funding: No funding was received for the preparation of […]

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Professional Liability for Forensic Activities:  Liability Without a Treatment Relationship

Professional Liability for Forensic Activities: Liability Without a Treatment Relationship

| August 1, 2016 | 0 Comments

by Donna Vanderpool, MBA, JD Ms. Vanderpool is Vice President of Risk Management at PRMS, Inc., Arlington, Virginia. Innov Clin Neurosci. 2016;13(7–8):41–44 This ongoing column is dedicated to providing information to our readers on managing legal risks associated with medical practice. We invite questions from our readers. The answers are provided by PRMS, Inc. (www.prms.com), […]

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Fahr’s Disease or Fahr’s Syndrome?

Fahr’s Disease or Fahr’s Syndrome?

| August 1, 2016 | 0 Comments

by Malathi Latha Perugula, MD, and Steven Lippmann, MD The authors are from the Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, Louisville, Kentucky. Innov Clin Neurosci. 2016;13(7–8):45–46 This column series compares neurological conditions that pose differential challenges in diagnoses. Funding: No funding was provided for the preparation of this article. […]

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