Innovations in Clinical Neuroscience

Providing evidence-based information in a practical, easy-to-read format for practicing clinicians, investigators, industry scientists, and other entities involved in the field of neuroscience

 

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VOLUME 16, ISSUE 7–8, JULY-AUGUST 2019

Editorial Message and Issue Highlights–Vol. 16, No. 7–8, July-August 2019

Editorial Message and Issue Highlights–Vol. 16, No. 7–8, July-August 2019

Dear Colleagues: Welcome to the July–August 2019 edition of Innovations in Clinical Neuroscience (ICNS). We start this issue with a meta-analysis by Whitlock, Woodward, and Alexander titled, “Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies.” Here, the authors investigated the accuracy of the popular theory that placebo […]

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Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies

Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies

by Mark E. Whitlock, PhD; Philip W. Woodward, MPhil; and Robert C. Alexander, MD Dr. Whitlock is BioStatistics Head of Internal Medicine, Early Clinical Development, for Pfizer in Cambridge, United Kingdom. Mr. Woodward is an independent statistics consultant in Newmarket, United Kingdom. Dr. Alexander is with Takeda Pharmaceuticals International Company in Cambridge, Massachusetts. Funding: No […]

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High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure

High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure

by Megan K. Skelly, PharmD, BCPS; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; and Claudia Lee, MD Drs. Skelly, Demler, and Lee are with the State University at Buffalo (SUNY) School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice in Buffalo, New York and Drs. Demler and Lee are also with New York […]

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Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child

Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child

by Catherine Butz, PhD; Cindy Iske, MS, OTR/L; Natalie Truba, PhD; and Kristen Trott, PhD Drs. Butz, Truba, and Trott are with the Psychology Department, and Ms. Iske is Program Manager for the Rehabilitation Unit, Physical Medicine and Rehabilitation Service, at Nationwide Children’s Hospital in Columbus, Ohio. Funding: No funding was provided. Disclosures: The authors […]

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The Very Important Patient

The Very Important Patient

by Danielle Gainer, MD, and Allison E. Cowan, MD Dr. Gainer is Assistant Professor, and Dr. Cowan is Associate Professor, in the Department of Psychiatry at Wright State University in Dayton, Ohio. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Department editors: Julie […]

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Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy

Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy

by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine at Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine at Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided. Disclosures: The authors have no conflicts […]

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THE NEUROSCIENCE REPORT

The Neuroscience Report—Vol. 54 (May 17, 2019): Migraines

The Neuroscience Report—Vol. 54 (May 17, 2019): Migraines

Welcome to The Neuroscience Report, where we highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Migraines 5 Journal Articles Understanding the nature of psychiatric comorbidity in migraine: a systematic […]

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The Neuroscience Report—Vol. 53 (August 14, 2018): Binge Eating Disorders

The Neuroscience Report—Vol. 53 (August 14, 2018): Binge Eating Disorders

Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information.   This week’s topic: Binge Eating Disorder   5 Journal Articles Binge eating, trauma, and suicide attempt in community […]

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The Neuroscience Report—Vol. 52 (April 11, 2018): Migraines

The Neuroscience Report—Vol. 52 (April 11, 2018): Migraines

Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Migraines 5 Journal Articles Spotlight on Anti-CGRP monoclonal antibodies in migraine: the clinical evidence to date […]

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The Neuroscience Report—Vol. 51 (December 28, 2017): New Discoveries in Neurodegenerative Diseases

The Neuroscience Report—Vol. 51 (December 28, 2017): New Discoveries in Neurodegenerative Diseases

Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Discoveries in Neurodegenerative Diseases 5 Journal Articles Pathogenesis and […]

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The Neuroscience Report—Vol. 50 (December 20, 2017): Advances in Neuroscience

The Neuroscience Report—Vol. 50 (December 20, 2017): Advances in Neuroscience

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Advances […]

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The Neuroscience Report—Vol. 49 (December 11, 2017): Neurological Disorders

The Neuroscience Report—Vol. 49 (December 11, 2017): Neurological Disorders

The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Neurological […]

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SPECIAL ISSUES AND SUPPLEMENTS

Hot Topics in Multiple Sclerosis

Hot Topics in Multiple Sclerosis

Click the cover below to access the digital editions of Hot Topics in Multiple Sclerosis! December 2018

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CNS Summit 2018 Abstracts of Poster Presentations

CNS Summit 2018 Abstracts of Poster Presentations

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The 30th Anniversary of PANSS Special Edition

The 30th Anniversary of PANSS Special Edition

[See sliding content bar above or scroll to bottom of page for complete list of articles included in this special edition of ICNS] Dear Colleagues: Thirty years ago, the Positive and Negative Syndrome Scale (PANSS) was developed and published by Stanley Kay, Abraham Fiszbein, and Lewis Opler to identify the presence and severity of psychopathology […]

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CNS Summit 2017 Abstracts of Poster Presentations

CNS Summit 2017 Abstracts of Poster Presentations

Innov Clin Neurosci. 2017;14(11–12)S1—S20

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CNS Summit 2016 Abstracts of Poster Presentations

CNS Summit 2016 Abstracts of Poster Presentations

Innov Clin Neurosci. 2017;14(1–2)3–23 A MESSAGE FROM THE EDITOR Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that was presented during CNS Summit 2016, which was held October 27 […]

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Supplement to November–December 2015 Issue: Abstracts of Poster Presentations: CNS Summit 2015

Supplement to November–December 2015 Issue: Abstracts of Poster Presentations: CNS Summit 2015

October 7–11, 2015 Boca Raton, Florida Innov Clin Neurosci. 2015;12(11–12 Suppl C):3–17 CNS Drug Compounds Synthesis of carnitine analogues for inhibition of carnitine palmitoyltransferase Presenters: Bornstein J, Garneau-Tsodikova S Affiliations: University of Michigan Life Sciences Institute Background: Type 2 diabetes (T2DM) carries a markedly elevated risk of cerebrovascular disease. Carnitine plays a key role transporting […]

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Recent Posts

Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage

| July 1, 2019

by Yue Deng, MSc; Brianna M. Marsh, BSc student; and Jackob Moskovitz, PhD Mr. Deng, Ms. Marsh, and Dr. Moskovitz are with the Department of Pharmacology and Toxicology at the School of Pharmacy, University of Kansas in Lawrence, Kansas. Funding: Support for the studies were provided by the KU ADC P30 AG035982 and the Landon […]

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Risk Management: Communicating with Family Members and Other Caregivers

Risk Management: Communicating with Family Members and Other Caregivers

| July 1, 2019

by Charles D. Cash, JD, LLM Mr. Cash is Assistant Vice President at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. This ongoing column is dedicated to providing information to our […]

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Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube

Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube

| July 1, 2019

Dear Editor: Social media platforms are increasingly used to disseminate health promotion and patient education.1–5 Impressions click-through rate (CTR) is the number of clicks on a health promotion and/or patient education ad, divided by the times the ad was shown on a social media platform. A recent study explored the practicality of Facebook advertising to […]

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