Review

The Role of Transcranial Magnetic Stimulation as a Surrogate Marker of Disease Activity in Patients with Multiple Sclerosis: A Literature Review
by Muhannad M. Alsharidah, MBBS; Mohammad Uzair, BS; Sarah S. Alseneidi, MBBS; Afnan A. Alkharan, MBBS; Reem Fahd Bunyan, MBBS; and Shahid Bashir, PhD Drs. Alsharidah and Alseneidi are with the College of Medicine, King Saud University in Riyadh, Saudi Arabia. Mr. Uzair is with the Department of Biological Sciences, Faculty of Basic and Applied […]

Pimavanserin in the Treatment of Parkinson’s Disease Psychosis: Meta-analysis and Meta-regression of Randomized Clinical Trials
by Zeeshan Mansuri, MD, MPH; Abhishek Reddy, MD; Ramu Vadukapuram, MD; Chintan Trivedi, MD, MPH; and Amy Amara, MD, PhD Dr. Mansuri is with the Department of Psychiatry, Boston Children’s Hospital/Harvard Medical School in Boston, Massachusetts. Dr. Reddy is with the Department of Psychiatry, Virginia Tech Carilion School of Medicine in Roanoke, Virginia. Dr. Vadukapuram is with […]

Managing Psychiatric Symptoms in Patients with Complex Regional Pain Syndrome
by Jonathan R. Scarff, MD Dr. Scarff is with Lexington Veterans Affairs Medical Center in Lexington, Kentucky. Funding: No funding was provided for this study. Disclosures: The author has no conflicts of interest relevant to the content of this article Innov Clin Neurosci. 2022;19(1–3):56–59. ABSTRACT: Complex regional pain syndrome (CRPS) is a rare but […]

Using Artificial Intelligence-based Methods to Address the Placebo Response in Clinical Trials
by Erica A. Smith, PhD; William P. Horan, PhD; Dominique Demolle, PhD; Peter Schueler, MD; Dong-Jing Fu, MD, PhD; Ariana E. Anderson, PhD; Joseph Geraci, MSc, PhD; Florence Butlen-Ducuing, MD, PhD; Jasmine Link, MS; Ni A. Khin, MD; Robert Morlock, PhD; and Larry D. Alphs, MD, PhD Drs. Smith and Demolle are with Cognivia in Mont St. […]

Clinician- and Patient-reported Endpoints in CNS Orphan Drug Clinical Trials: ISCTM Position Paper on Best Practices for Endpoint Selection, Validation, Training, and Standardization
by Joan Busner, PhD; Gahan Pandina, PhD; Silvia Zaragoza domingo PhD; Anna-Karin Berger PhD; Maria T. Acosta, MD; Nahome Fisseha, PharmD; Joseph Horrigan, MD; Jelena Ivkovic, MD; William Jacobson, PhD; Dennis Revicki, PhD; and Victoria Villalta-Gil, PhD, MSc All authors are members of the ISCTM Working Group for Rare Disease/Orphan Drug Development; Drs. Busner and Pandina […]

Latency to First Event is Shorter in Psychogenic Non-epileptic Seizures Than in Epileptic Seizures in an Epilepsy Monitoring Unit
by Vishwanath Sagi MBBS, MPH; Jaime Shoup MD; Ravikiran Chilukuri; and M. Steven Evans MD Drs. Sagi and Evans are with the Department of Neurology at the University of Louisville in Louisville, Kentucky. Drs. Shoup and Chilukuri are with the University of Louisville School of Medicine in Louisville, Kentucky. FUNDING: No funding was provided for […]

Neurological Aspects of Corona Virus Infectious Disease 2019 (COVID-19)
by Nitin Butala Dr. Butala is a Neurologist and Neurophysiologist at Baptist Health in Jacksonville, Florida and an Assistant professor of Neurology at the Lake Erie College of Osteopathic Medicine in Bradenton, Florida FUNDING: No funding was provided. DISCLOSURES: The author has no conflicts of interest relevant to the content of this […]